| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTB | AFDN | ENSPPYP00000019427 | ENSPPYP00000019236 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | AFDN isoform 9. | 0.933 |
| ACTB | CTNNA1 | ENSPPYP00000019427 | ENSPPYP00000017700 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | CTNNA1 isoform 1. | 0.927 |
| ACTB | CTNNA2 | ENSPPYP00000019427 | ENSPPYP00000013655 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of star [...] | 0.927 |
| ACTB | OCLN | ENSPPYP00000019427 | ENSPPYP00000017356 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. | 0.529 |
| ACTB | TJP1 | ENSPPYP00000019427 | ENSPPYP00000007122 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | TJP1 isoform 1; Belongs to the MAGUK family. | 0.963 |
| AFDN | ACTB | ENSPPYP00000019236 | ENSPPYP00000019427 | AFDN isoform 9. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.933 |
| AFDN | CTNNA1 | ENSPPYP00000019236 | ENSPPYP00000017700 | AFDN isoform 9. | CTNNA1 isoform 1. | 0.979 |
| AFDN | CTNNA2 | ENSPPYP00000019236 | ENSPPYP00000013655 | AFDN isoform 9. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of star [...] | 0.978 |
| AFDN | F11R | ENSPPYP00000019236 | ENSPPYP00000000723 | AFDN isoform 9. | F11R isoform 1. | 0.968 |
| AFDN | TJP1 | ENSPPYP00000019236 | ENSPPYP00000007122 | AFDN isoform 9. | TJP1 isoform 1; Belongs to the MAGUK family. | 0.975 |
| AFDN | TJP2 | ENSPPYP00000019236 | ENSPPYP00000021587 | AFDN isoform 9. | TJP2 isoform 3; Belongs to the MAGUK family. | 0.975 |
| CGN | F11R | ENSPPYP00000001009 | ENSPPYP00000000723 | CGN isoform 4. | F11R isoform 1. | 0.824 |
| CGN | MARVELD2 | ENSPPYP00000001009 | ENSPPYP00000017355 | CGN isoform 4. | MARVEL domain containing 2. | 0.493 |
| CGN | OCLN | ENSPPYP00000001009 | ENSPPYP00000017356 | CGN isoform 4. | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. | 0.479 |
| CGN | TJP1 | ENSPPYP00000001009 | ENSPPYP00000007122 | CGN isoform 4. | TJP1 isoform 1; Belongs to the MAGUK family. | 0.997 |
| CGN | TJP2 | ENSPPYP00000001009 | ENSPPYP00000021587 | CGN isoform 4. | TJP2 isoform 3; Belongs to the MAGUK family. | 0.748 |
| CTNNA1 | ACTB | ENSPPYP00000017700 | ENSPPYP00000019427 | CTNNA1 isoform 1. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.927 |
| CTNNA1 | AFDN | ENSPPYP00000017700 | ENSPPYP00000019236 | CTNNA1 isoform 1. | AFDN isoform 9. | 0.979 |
| CTNNA1 | CTNNA2 | ENSPPYP00000017700 | ENSPPYP00000013655 | CTNNA1 isoform 1. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of star [...] | 0.989 |
| CTNNA1 | TJP1 | ENSPPYP00000017700 | ENSPPYP00000007122 | CTNNA1 isoform 1. | TJP1 isoform 1; Belongs to the MAGUK family. | 0.972 |
