STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TJP1TJP1 isoform 1; Belongs to the MAGUK family. (1746 aa)    
Predicted Functional Partners:
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
   
 
 0.995
F11R
F11R isoform 1.
   
 0.989
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
 0.989
CGN
CGN isoform 4.
   
 0.988
CLDN7
Claudin-7.
   
 
 0.968
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 
 0.967
KIRREL1
Kirre like nephrin family adhesion molecule 1.
    
 0.951
WWTR1
WW domain containing transcription regulator 1.
   
 0.950
MARVELD2
MARVEL domain containing 2.
   
 
 0.911
CTNNB1
CTNNB1 isoform 2.
    
 0.878
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.