DPH6 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSMD3	DPH6	ENSPPYP00000021124	ENSPPYP00000007166	CSMD3 isoform 5.	Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.	0.569
CSMD3	MYO3B	ENSPPYP00000021124	ENSPPYP00000014421	CSMD3 isoform 5.	MYO3B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.552
CSMD3	PPP1R1C	ENSPPYP00000021124	ENSPPYP00000014513	CSMD3 isoform 5.	Protein phosphatase 1 regulatory subunit 1C; May increase cell susceptibility to TNF-induced apoptosis. Belongs to the protein phosphatase inhibitor 1 family.	0.555
DPH1	DPH2	ENSPPYP00000008774	ENSPPYP00000001667	DPH1 isoform 1.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	0.991
DPH1	DPH3	ENSPPYP00000008774	ENSPPYP00000015754	DPH1 isoform 1.	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	0.986
DPH1	DPH5	ENSPPYP00000008774	ENSPPYP00000001285	DPH1 isoform 1.	Diphthamide biosynthesis 5.	0.911
DPH1	DPH6	ENSPPYP00000008774	ENSPPYP00000007166	DPH1 isoform 1.	Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.	0.628
DPH1	DPH7	ENSPPYP00000008774	ENSPPYP00000024367	DPH1 isoform 1.	DPH7 isoform 1.	0.656
DPH1	EEF2	ENSPPYP00000008774	ENSPPYP00000010534	DPH1 isoform 1.	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	0.959
DPH2	DPH1	ENSPPYP00000001667	ENSPPYP00000008774	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	DPH1 isoform 1.	0.991
DPH2	DPH3	ENSPPYP00000001667	ENSPPYP00000015754	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	0.994
DPH2	DPH5	ENSPPYP00000001667	ENSPPYP00000001285	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	Diphthamide biosynthesis 5.	0.939
DPH2	DPH6	ENSPPYP00000001667	ENSPPYP00000007166	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.	0.633
DPH2	DPH7	ENSPPYP00000001667	ENSPPYP00000024367	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	DPH7 isoform 1.	0.657
DPH2	EEF2	ENSPPYP00000001667	ENSPPYP00000010534	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]	0.970
DPH3	DPH1	ENSPPYP00000015754	ENSPPYP00000008774	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	DPH1 isoform 1.	0.986
DPH3	DPH2	ENSPPYP00000015754	ENSPPYP00000001667	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily.	0.994
DPH3	DPH5	ENSPPYP00000015754	ENSPPYP00000001285	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	Diphthamide biosynthesis 5.	0.726
DPH3	DPH6	ENSPPYP00000015754	ENSPPYP00000007166	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.	0.618
DPH3	DPH7	ENSPPYP00000015754	ENSPPYP00000024367	DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).	DPH7 isoform 1.	0.533