SPPL2A protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP4E1	CR201_G0040674	ENSPPYP00000007336	ENSPPYP00000019732	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	MRPS24 isoform 2.	0.457
AP4E1	GGPS1	ENSPPYP00000007336	ENSPPYP00000000097	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	0.484
AP4E1	HYI	ENSPPYP00000007336	ENSPPYP00000001674	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	0.592
AP4E1	MRPS24	ENSPPYP00000007336	ENSPPYP00000022429	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	MRPS24 isoform 3.	0.457
AP4E1	SPPL2A	ENSPPYP00000007336	ENSPPYP00000007335	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	Signal peptide peptidase like 2A.	0.527
CR201_G0040674	AP4E1	ENSPPYP00000019732	ENSPPYP00000007336	MRPS24 isoform 2.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.457
CR201_G0040674	HYI	ENSPPYP00000019732	ENSPPYP00000001674	MRPS24 isoform 2.	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	0.487
CR201_G0040674	SPPL2A	ENSPPYP00000019732	ENSPPYP00000007335	MRPS24 isoform 2.	Signal peptide peptidase like 2A.	0.484
GABPB1	SPPL2A	ENSPPYP00000007331	ENSPPYP00000007335	GABPB1 isoform 1.	Signal peptide peptidase like 2A.	0.497
GGPS1	AP4E1	ENSPPYP00000000097	ENSPPYP00000007336	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.484
GGPS1	HYI	ENSPPYP00000000097	ENSPPYP00000001674	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	0.515
GGPS1	SPPL2A	ENSPPYP00000000097	ENSPPYP00000007335	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	Signal peptide peptidase like 2A.	0.482
HYI	AP4E1	ENSPPYP00000001674	ENSPPYP00000007336	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.592
HYI	CR201_G0040674	ENSPPYP00000001674	ENSPPYP00000019732	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	MRPS24 isoform 2.	0.487
HYI	GGPS1	ENSPPYP00000001674	ENSPPYP00000000097	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	GGPS1 isoform 1; Belongs to the FPP/GGPP synthase family.	0.515
HYI	MRPS24	ENSPPYP00000001674	ENSPPYP00000022429	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	MRPS24 isoform 3.	0.487
HYI	SPPL2A	ENSPPYP00000001674	ENSPPYP00000007335	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	Signal peptide peptidase like 2A.	0.585
MRPS24	AP4E1	ENSPPYP00000022429	ENSPPYP00000007336	MRPS24 isoform 3.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.457
MRPS24	HYI	ENSPPYP00000022429	ENSPPYP00000001674	MRPS24 isoform 3.	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family.	0.487
MRPS24	SPPL2A	ENSPPYP00000022429	ENSPPYP00000007335	MRPS24 isoform 3.	Signal peptide peptidase like 2A.	0.484