| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0044248 | HDAC1 | ENSPPYP00000010505 | ENSPPYP00000001838 | AES isoform 2. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.590 |
| CR201_G0044248 | LEF1 | ENSPPYP00000010505 | ENSPPYP00000016739 | AES isoform 2. | Lymphoid enhancer binding factor 1. | 0.628 |
| CR201_G0044248 | RIPPLY1 | ENSPPYP00000010505 | ENSPPYP00000023064 | AES isoform 2. | RIPPLY1 isoform 2. | 0.827 |
| CR201_G0044248 | TCF7 | ENSPPYP00000010505 | ENSPPYP00000017648 | AES isoform 2. | TCF7 isoform 6. | 0.586 |
| CR201_G0044248 | TLE1 | ENSPPYP00000010505 | ENSPPYP00000021643 | AES isoform 2. | TLE1 isoform 1. | 0.955 |
| CR201_G0044248 | TLE2 | ENSPPYP00000010505 | ENSPPYP00000010504 | AES isoform 2. | TLE2 isoform 1. | 0.939 |
| CR201_G0044248 | TLE3 | ENSPPYP00000010505 | ENSPPYP00000007485 | AES isoform 2. | TLE family member 3, transcriptional corepressor. | 0.861 |
| CR201_G0044248 | TLE4 | ENSPPYP00000010505 | ENSPPYP00000021638 | AES isoform 2. | TLE4 isoform 4. | 0.939 |
| CR201_G0044248 | XIAP | ENSPPYP00000010505 | ENSPPYP00000023167 | AES isoform 2. | XIAP isoform 2. | 0.644 |
| HDAC1 | CR201_G0044248 | ENSPPYP00000001838 | ENSPPYP00000010505 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | AES isoform 2. | 0.590 |
| HDAC1 | LEF1 | ENSPPYP00000001838 | ENSPPYP00000016739 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | Lymphoid enhancer binding factor 1. | 0.641 |
| HDAC1 | RBPJ | ENSPPYP00000001838 | ENSPPYP00000016373 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | Recombining binding protein suppressor of hairless; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling [...] | 0.955 |
| HDAC1 | TCF7 | ENSPPYP00000001838 | ENSPPYP00000017648 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | TCF7 isoform 6. | 0.564 |
| HDAC1 | TLE1 | ENSPPYP00000001838 | ENSPPYP00000021643 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | TLE1 isoform 1. | 0.964 |
| HDAC1 | TLE2 | ENSPPYP00000001838 | ENSPPYP00000010504 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | TLE2 isoform 1. | 0.590 |
| HDAC1 | TLE3 | ENSPPYP00000001838 | ENSPPYP00000007485 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | TLE family member 3, transcriptional corepressor. | 0.935 |
| HDAC1 | TLE4 | ENSPPYP00000001838 | ENSPPYP00000021638 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | TLE4 isoform 4. | 0.914 |
| LEF1 | CR201_G0044248 | ENSPPYP00000016739 | ENSPPYP00000010505 | Lymphoid enhancer binding factor 1. | AES isoform 2. | 0.628 |
| LEF1 | HDAC1 | ENSPPYP00000016739 | ENSPPYP00000001838 | Lymphoid enhancer binding factor 1. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.641 |
| LEF1 | TCF7 | ENSPPYP00000016739 | ENSPPYP00000017648 | Lymphoid enhancer binding factor 1. | TCF7 isoform 6. | 0.968 |
