STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEXABeta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (529 aa)    
Predicted Functional Partners:
HEXB
Beta-hexosaminidase.
  
 
0.998
GLB1
Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family.
  
 
 0.941
GLA
Alpha-galactosidase.
  
 
 0.940
NAGA
Alpha-galactosidase.
   
 
 0.931
CHIA
Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.
    
 0.929
ENSPPYP00000001206
LOW QUALITY PROTEIN: acidic mammalian chitinase-like.
    
 0.929
HEXDC
HEXDC isoform 8.
     
 0.927
B4GALNT1
Beta-1,4 N-acetylgalactosaminyltransferase.
     
 0.926
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
   
 0.920
NAGK
N-acetylglucosamine kinase.
  
 
 0.911
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (28%) [HD]