STRA6 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB6	SALL2	ENSPPYP00000014747	ENSPPYP00000006370	ATP binding cassette subfamily B member 6 (Langereis blood group).	SALL2 isoform 1.	0.408
ABCB6	STRA6	ENSPPYP00000014747	ENSPPYP00000007525	ATP binding cassette subfamily B member 6 (Langereis blood group).	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.481
EPHA1	STRA6	ENSPPYP00000020327	ENSPPYP00000007525	EPHA1 isoform 1.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.485
LRAT	RBP1	ENSPPYP00000016922	ENSPPYP00000015837	LRAT isoform 2.	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.851
LRAT	RDH10	ENSPPYP00000016922	ENSPPYP00000020945	LRAT isoform 2.	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.944
LRAT	STRA6	ENSPPYP00000016922	ENSPPYP00000007525	LRAT isoform 2.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.487
RARA	RARS1	ENSPPYP00000009510	ENSPPYP00000017935	RARA isoform 2.	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	0.756
RARA	RBP1	ENSPPYP00000009510	ENSPPYP00000015837	RARA isoform 2.	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.450
RARA	STRA6	ENSPPYP00000009510	ENSPPYP00000007525	RARA isoform 2.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.488
RARS1	RARA	ENSPPYP00000017935	ENSPPYP00000009510	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	RARA isoform 2.	0.756
RARS1	RBP1	ENSPPYP00000017935	ENSPPYP00000015837	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.473
RARS1	RBP4	ENSPPYP00000017935	ENSPPYP00000002889	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.	0.692
RARS1	RDH10	ENSPPYP00000017935	ENSPPYP00000020945	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.540
RARS1	STRA6	ENSPPYP00000017935	ENSPPYP00000007525	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.621
RBP1	LRAT	ENSPPYP00000015837	ENSPPYP00000016922	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	LRAT isoform 2.	0.851
RBP1	RARA	ENSPPYP00000015837	ENSPPYP00000009510	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	RARA isoform 2.	0.450
RBP1	RARS1	ENSPPYP00000015837	ENSPPYP00000017935	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.	0.473
RBP1	RBP4	ENSPPYP00000015837	ENSPPYP00000002889	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.	0.722
RBP1	RDH10	ENSPPYP00000015837	ENSPPYP00000020945	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.498
RBP1	STRA6	ENSPPYP00000015837	ENSPPYP00000007525	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.865