STRA6 protein (Pongo abelii) - STRING interaction network

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STRA6

Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...] (666 aa)

Predicted Functional Partners:

RBP1

0.882

TTR

0.765

RBP4

0.758

LRAT

0.673

CALML5

0.662

CALML3

0.662

CALML6

0.600

CALML4

0.600

RARA

0.564

CYP26A1

0.546

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALML3	CALML4	ENSPPYP00000002383	ENSPPYP00000007472	CALML3 isoform 1; Belongs to the calmodulin family.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.945
CALML3	CALML5	ENSPPYP00000002383	ENSPPYP00000002382	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin like 5.	0.949
CALML3	CALML6	ENSPPYP00000002383	ENSPPYP00000002306	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin like 6.	0.943
CALML3	STRA6	ENSPPYP00000002383	ENSPPYP00000007525	CALML3 isoform 1; Belongs to the calmodulin family.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.662
CALML4	CALML3	ENSPPYP00000007472	ENSPPYP00000002383	LOW QUALITY PROTEIN: calmodulin-like protein 4.	CALML3 isoform 1; Belongs to the calmodulin family.	0.945
CALML4	CALML5	ENSPPYP00000007472	ENSPPYP00000002382	LOW QUALITY PROTEIN: calmodulin-like protein 4.	Calmodulin like 5.	0.946
CALML4	CALML6	ENSPPYP00000007472	ENSPPYP00000002306	LOW QUALITY PROTEIN: calmodulin-like protein 4.	Calmodulin like 6.	0.943
CALML4	STRA6	ENSPPYP00000007472	ENSPPYP00000007525	LOW QUALITY PROTEIN: calmodulin-like protein 4.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.600
CALML5	CALML3	ENSPPYP00000002382	ENSPPYP00000002383	Calmodulin like 5.	CALML3 isoform 1; Belongs to the calmodulin family.	0.949
CALML5	CALML4	ENSPPYP00000002382	ENSPPYP00000007472	Calmodulin like 5.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.946
CALML5	CALML6	ENSPPYP00000002382	ENSPPYP00000002306	Calmodulin like 5.	Calmodulin like 6.	0.945
CALML5	STRA6	ENSPPYP00000002382	ENSPPYP00000007525	Calmodulin like 5.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.662
CALML6	CALML3	ENSPPYP00000002306	ENSPPYP00000002383	Calmodulin like 6.	CALML3 isoform 1; Belongs to the calmodulin family.	0.943
CALML6	CALML4	ENSPPYP00000002306	ENSPPYP00000007472	Calmodulin like 6.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.943
CALML6	CALML5	ENSPPYP00000002306	ENSPPYP00000002382	Calmodulin like 6.	Calmodulin like 5.	0.945
CALML6	STRA6	ENSPPYP00000002306	ENSPPYP00000007525	Calmodulin like 6.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.600
CYP26A1	LRAT	ENSPPYP00000002884	ENSPPYP00000016922	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	LRAT isoform 2.	0.556
CYP26A1	RARA	ENSPPYP00000002884	ENSPPYP00000009510	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	RARA isoform 2.	0.566
CYP26A1	RBP1	ENSPPYP00000002884	ENSPPYP00000015837	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	RBP1 isoform 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	0.571
CYP26A1	STRA6	ENSPPYP00000002884	ENSPPYP00000007525	Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.	Receptor for retinol uptake STRA6; Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT- dependent generation of retinol metabolites that then trigger activation of JAK2 and i [...]	0.546

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