| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0034363 | GRB2 | ENSPPYP00000024652 | ENSPPYP00000009686 | SH2B1 isoform 11. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.982 |
| CR201_G0034363 | NTRK3 | ENSPPYP00000024652 | ENSPPYP00000007657 | SH2B1 isoform 11. | Tyrosine-protein kinase receptor. | 0.934 |
| GRB2 | CR201_G0034363 | ENSPPYP00000009686 | ENSPPYP00000024652 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | SH2B1 isoform 11. | 0.982 |
| GRB2 | NTRK3 | ENSPPYP00000009686 | ENSPPYP00000007657 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Tyrosine-protein kinase receptor. | 0.965 |
| GRB2 | PLCG1 | ENSPPYP00000009686 | ENSPPYP00000012298 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.977 |
| GRB2 | PLCG2 | ENSPPYP00000009686 | ENSPPYP00000008564 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.880 |
| GRB2 | PTPRS | ENSPPYP00000009686 | ENSPPYP00000010566 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | PTPRS isoform 2. | 0.585 |
| GRB2 | SH2B2 | ENSPPYP00000009686 | ENSPPYP00000019567 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | SH2B2 isoform 1. | 0.968 |
| GRB2 | SHC1 | ENSPPYP00000009686 | ENSPPYP00000000893 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.999 |
| GRB2 | SHC3 | ENSPPYP00000009686 | ENSPPYP00000021691 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | SHC3 isoform 1. | 0.994 |
| NGF | NTRK3 | ENSPPYP00000001154 | ENSPPYP00000007657 | NGF isoform 1; Belongs to the NGF-beta family. | Tyrosine-protein kinase receptor. | 0.977 |
| NGF | PLCG1 | ENSPPYP00000001154 | ENSPPYP00000012298 | NGF isoform 1; Belongs to the NGF-beta family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.423 |
| NTF3 | NTRK3 | ENSPPYP00000004761 | ENSPPYP00000007657 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | Tyrosine-protein kinase receptor. | 0.990 |
| NTF3 | PLCG1 | ENSPPYP00000004761 | ENSPPYP00000012298 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.432 |
| NTRK3 | CR201_G0034363 | ENSPPYP00000007657 | ENSPPYP00000024652 | Tyrosine-protein kinase receptor. | SH2B1 isoform 11. | 0.934 |
| NTRK3 | GRB2 | ENSPPYP00000007657 | ENSPPYP00000009686 | Tyrosine-protein kinase receptor. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.965 |
| NTRK3 | NGF | ENSPPYP00000007657 | ENSPPYP00000001154 | Tyrosine-protein kinase receptor. | NGF isoform 1; Belongs to the NGF-beta family. | 0.977 |
| NTRK3 | NTF3 | ENSPPYP00000007657 | ENSPPYP00000004761 | Tyrosine-protein kinase receptor. | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. | 0.990 |
| NTRK3 | PLCG1 | ENSPPYP00000007657 | ENSPPYP00000012298 | Tyrosine-protein kinase receptor. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.971 |
| NTRK3 | PLCG2 | ENSPPYP00000007657 | ENSPPYP00000008564 | Tyrosine-protein kinase receptor. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.962 |
