KCTD5 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Cooccurrence

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Experiments

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[Homology]

Score

KCTD5

KCTD5 isoform 1. (197 aa)

Predicted Functional Partners:

CUL3

0.744

CUL1

0.551

CACUL1

0.504

KCTD17

0.477

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACUL1	KCTD17	ENSPPYP00000003147	ENSPPYP00000013148	CACUL1 isoform 2; Belongs to the cullin family.	Potassium channel tetramerization domain containing 17.	0.504
CACUL1	KCTD5	ENSPPYP00000003147	ENSPPYP00000007928	CACUL1 isoform 2; Belongs to the cullin family.	KCTD5 isoform 1.	0.504
CUL1	CUL3	ENSPPYP00000020352	ENSPPYP00000014786	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	CUL3 isoform 1; Belongs to the cullin family.	0.851
CUL1	KCTD17	ENSPPYP00000020352	ENSPPYP00000013148	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	Potassium channel tetramerization domain containing 17.	0.551
CUL1	KCTD5	ENSPPYP00000020352	ENSPPYP00000007928	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	KCTD5 isoform 1.	0.551
CUL3	CUL1	ENSPPYP00000014786	ENSPPYP00000020352	CUL3 isoform 1; Belongs to the cullin family.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.851
CUL3	KCTD17	ENSPPYP00000014786	ENSPPYP00000013148	CUL3 isoform 1; Belongs to the cullin family.	Potassium channel tetramerization domain containing 17.	0.954
CUL3	KCTD5	ENSPPYP00000014786	ENSPPYP00000007928	CUL3 isoform 1; Belongs to the cullin family.	KCTD5 isoform 1.	0.744
KCTD17	CACUL1	ENSPPYP00000013148	ENSPPYP00000003147	Potassium channel tetramerization domain containing 17.	CACUL1 isoform 2; Belongs to the cullin family.	0.504
KCTD17	CUL1	ENSPPYP00000013148	ENSPPYP00000020352	Potassium channel tetramerization domain containing 17.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.551
KCTD17	CUL3	ENSPPYP00000013148	ENSPPYP00000014786	Potassium channel tetramerization domain containing 17.	CUL3 isoform 1; Belongs to the cullin family.	0.954
KCTD17	KCTD5	ENSPPYP00000013148	ENSPPYP00000007928	Potassium channel tetramerization domain containing 17.	KCTD5 isoform 1.	0.477
KCTD5	CACUL1	ENSPPYP00000007928	ENSPPYP00000003147	KCTD5 isoform 1.	CACUL1 isoform 2; Belongs to the cullin family.	0.504
KCTD5	CUL1	ENSPPYP00000007928	ENSPPYP00000020352	KCTD5 isoform 1.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.551
KCTD5	CUL3	ENSPPYP00000007928	ENSPPYP00000014786	KCTD5 isoform 1.	CUL3 isoform 1; Belongs to the cullin family.	0.744
KCTD5	KCTD17	ENSPPYP00000007928	ENSPPYP00000013148	KCTD5 isoform 1.	Potassium channel tetramerization domain containing 17.	0.477