STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKMYT1PKMYT1 isoform 10; Belongs to the protein kinase superfamily. (499 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...]
  
0.994
PLK1
Serine/threonine-protein kinase PLK.
   
0.986
CCNB1
CCNB1 isoform 1; Belongs to the cyclin family.
   
 0.942
MOS
MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.913
RPS6KA1
Ribosomal protein S6 kinase.
     
 
0.900
RPS6KA2
Ribosomal protein S6 kinase.
     
 
0.900
RPS6KA3
Ribosomal protein S6 kinase.
     
 
0.900
RPS6KA6
Ribosomal protein S6 kinase.
     
 
0.900
CCNA2
CCNA2 isoform 1; Belongs to the cyclin family.
   
 0.890
CCNB2
CCNB2 isoform 1; Belongs to the cyclin family.
   
 0.820
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.