| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCY3 | ADCY6 | ENSPPYP00000014065 | ENSPPYP00000005099 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.943 |
| ADCY3 | ADCY9 | ENSPPYP00000014065 | ENSPPYP00000007976 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.959 |
| ADCY3 | GNAI2 | ENSPPYP00000014065 | ENSPPYP00000015499 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAI2 isoform 1. | 0.969 |
| ADCY3 | GNAI3 | ENSPPYP00000014065 | ENSPPYP00000001241 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] | 0.959 |
| ADCY3 | GNAL | ENSPPYP00000014065 | ENSPPYP00000010095 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAL isoform 3. | 0.996 |
| ADCY3 | GNAO1 | ENSPPYP00000014065 | ENSPPYP00000008317 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAO1 isoform 1. | 0.956 |
| ADCY3 | GNAS | ENSPPYP00000014065 | ENSPPYP00000012485 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAS isoform 2. | 0.987 |
| ADCY3 | PRKACB | ENSPPYP00000014065 | ENSPPYP00000001400 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.948 |
| ADCY3 | PRKACG | ENSPPYP00000014065 | ENSPPYP00000021585 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.948 |
| ADCY3 | RAPGEF4 | ENSPPYP00000014065 | ENSPPYP00000014442 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Rap guanine nucleotide exchange factor 4. | 0.918 |
| ADCY6 | ADCY3 | ENSPPYP00000005099 | ENSPPYP00000014065 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | 0.943 |
| ADCY6 | ADCY9 | ENSPPYP00000005099 | ENSPPYP00000007976 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.951 |
| ADCY6 | GNAI2 | ENSPPYP00000005099 | ENSPPYP00000015499 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAI2 isoform 1. | 0.964 |
| ADCY6 | GNAI3 | ENSPPYP00000005099 | ENSPPYP00000001241 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] | 0.958 |
| ADCY6 | GNAL | ENSPPYP00000005099 | ENSPPYP00000010095 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAL isoform 3. | 0.759 |
| ADCY6 | GNAO1 | ENSPPYP00000005099 | ENSPPYP00000008317 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAO1 isoform 1. | 0.947 |
| ADCY6 | GNAS | ENSPPYP00000005099 | ENSPPYP00000012485 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | GNAS isoform 2. | 0.986 |
| ADCY6 | PRKACB | ENSPPYP00000005099 | ENSPPYP00000001400 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | PRKACB isoform 9; Belongs to the protein kinase superfamily. | 0.953 |
| ADCY6 | PRKACG | ENSPPYP00000005099 | ENSPPYP00000021585 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. | 0.953 |
| ADCY6 | RAPGEF4 | ENSPPYP00000005099 | ENSPPYP00000014442 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. | Rap guanine nucleotide exchange factor 4. | 0.941 |
