USP7 protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

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Score

USP7

USP7 isoform 8; Belongs to the peptidase C19 family. (1082 aa)

Predicted Functional Partners:

TP53

0.998

DAXX

0.996

UVSSA

0.993

GMPS

0.976

FOXO4

0.971

DNMT1

0.969

UHRF1

0.967

UBC

0.966

FOXO3

0.961

FOXO1

0.958

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAXX	DNMT1	ENSPPYP00000019339	ENSPPYP00000010706	Death domain associated protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.852
DAXX	TP53	ENSPPYP00000019339	ENSPPYP00000008923	Death domain associated protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.996
DAXX	UBC	ENSPPYP00000019339	ENSPPYP00000005811	Death domain associated protein.	UBC isoform 2.	0.441
DAXX	USP7	ENSPPYP00000019339	ENSPPYP00000008014	Death domain associated protein.	USP7 isoform 8; Belongs to the peptidase C19 family.	0.996
DNMT1	DAXX	ENSPPYP00000010706	ENSPPYP00000019339	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Death domain associated protein.	0.852
DNMT1	TP53	ENSPPYP00000010706	ENSPPYP00000008923	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.887
DNMT1	UBC	ENSPPYP00000010706	ENSPPYP00000005811	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	UBC isoform 2.	0.882
DNMT1	UHRF1	ENSPPYP00000010706	ENSPPYP00000010564	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	UHRF1 isoform 6.	0.999
DNMT1	USP7	ENSPPYP00000010706	ENSPPYP00000008014	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	USP7 isoform 8; Belongs to the peptidase C19 family.	0.969
FOXO1	FOXO3	ENSPPYP00000006042	ENSPPYP00000018917	FOXO1 isoform 1.	FOXO3 isoform 1.	0.992
FOXO1	FOXO4	ENSPPYP00000006042	ENSPPYP00000024155	FOXO1 isoform 1.	FOXO4 isoform 1.	0.462
FOXO1	TP53	ENSPPYP00000006042	ENSPPYP00000008923	FOXO1 isoform 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.794
FOXO1	USP7	ENSPPYP00000006042	ENSPPYP00000008014	FOXO1 isoform 1.	USP7 isoform 8; Belongs to the peptidase C19 family.	0.958
FOXO3	FOXO1	ENSPPYP00000018917	ENSPPYP00000006042	FOXO3 isoform 1.	FOXO1 isoform 1.	0.992
FOXO3	FOXO4	ENSPPYP00000018917	ENSPPYP00000024155	FOXO3 isoform 1.	FOXO4 isoform 1.	0.890
FOXO3	TP53	ENSPPYP00000018917	ENSPPYP00000008923	FOXO3 isoform 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.897
FOXO3	USP7	ENSPPYP00000018917	ENSPPYP00000008014	FOXO3 isoform 1.	USP7 isoform 8; Belongs to the peptidase C19 family.	0.961
FOXO4	FOXO1	ENSPPYP00000024155	ENSPPYP00000006042	FOXO4 isoform 1.	FOXO1 isoform 1.	0.462
FOXO4	FOXO3	ENSPPYP00000024155	ENSPPYP00000018917	FOXO4 isoform 1.	FOXO3 isoform 1.	0.890
FOXO4	TP53	ENSPPYP00000024155	ENSPPYP00000008923	FOXO4 isoform 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.884