| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCE1 | EPRS1 | ENSPPYP00000016865 | ENSPPYP00000000215 | ABCE1 isoform 1. | EPRS isoform 1. | 0.843 |
| ABCE1 | ETF1 | ENSPPYP00000016865 | ENSPPYP00000017698 | ABCE1 isoform 1. | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | 0.980 |
| ABCE1 | GSPT1 | ENSPPYP00000016865 | ENSPPYP00000008043 | ABCE1 isoform 1. | GSPT1 isoform 2. | 0.723 |
| ABCE1 | GSPT2 | ENSPPYP00000016865 | ENSPPYP00000022791 | ABCE1 isoform 1. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). | 0.723 |
| ABCE1 | UPF1 | ENSPPYP00000016865 | ENSPPYP00000010923 | ABCE1 isoform 1. | UPF1 isoform 2. | 0.479 |
| EPRS1 | ABCE1 | ENSPPYP00000000215 | ENSPPYP00000016865 | EPRS isoform 1. | ABCE1 isoform 1. | 0.843 |
| EPRS1 | ETF1 | ENSPPYP00000000215 | ENSPPYP00000017698 | EPRS isoform 1. | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | 0.821 |
| EPRS1 | GSPT1 | ENSPPYP00000000215 | ENSPPYP00000008043 | EPRS isoform 1. | GSPT1 isoform 2. | 0.823 |
| EPRS1 | GSPT2 | ENSPPYP00000000215 | ENSPPYP00000022791 | EPRS isoform 1. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). | 0.823 |
| EPRS1 | PABPC1 | ENSPPYP00000000215 | ENSPPYP00000021076 | EPRS isoform 1. | Polyadenylate-binding protein 1; Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region deter [...] | 0.454 |
| ETF1 | ABCE1 | ENSPPYP00000017698 | ENSPPYP00000016865 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | ABCE1 isoform 1. | 0.980 |
| ETF1 | EPRS1 | ENSPPYP00000017698 | ENSPPYP00000000215 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | EPRS isoform 1. | 0.821 |
| ETF1 | GSPT1 | ENSPPYP00000017698 | ENSPPYP00000008043 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | GSPT1 isoform 2. | 0.963 |
| ETF1 | GSPT2 | ENSPPYP00000017698 | ENSPPYP00000022791 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). | 0.963 |
| ETF1 | PABPC1 | ENSPPYP00000017698 | ENSPPYP00000021076 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | Polyadenylate-binding protein 1; Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region deter [...] | 0.618 |
| ETF1 | SMG1 | ENSPPYP00000017698 | ENSPPYP00000008072 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | SMG1 isoform 8; Belongs to the PI3/PI4-kinase family. | 0.965 |
| ETF1 | UPF1 | ENSPPYP00000017698 | ENSPPYP00000010923 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | UPF1 isoform 2. | 0.929 |
| ETF1 | ZGRF1 | ENSPPYP00000017698 | ENSPPYP00000016762 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | ZGRF1 isoform 9. | 0.860 |
| GSPT1 | ABCE1 | ENSPPYP00000008043 | ENSPPYP00000016865 | GSPT1 isoform 2. | ABCE1 isoform 1. | 0.723 |
| GSPT1 | EPRS1 | ENSPPYP00000008043 | ENSPPYP00000000215 | GSPT1 isoform 2. | EPRS isoform 1. | 0.823 |
