STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYH11MYH11 isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1794 aa)    
Predicted Functional Partners:
LMOD1
LMOD1 isoform 2.
   
 
 0.950
ACTG2
ACTG2 isoform 3.
   
 0.918
CR201_G0047951
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
  
 0.909
MYLK
MYLK isoform 5.
   
 0.856
MYL6
Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium (By similarity).
   
 0.833
MYL9
Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
   
 0.824
CR201_G0015086
CBFB isoform 2.
      
 0.814
TAGLN
Transgelin; Belongs to the calponin family.
   
  
 0.780
ACTA2
ACTA2 isoform 5.
   
 0.776
MYL1
MYL1 isoform 2.
   
 0.772
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.