| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD3E | GRAP2 | ENSPPYP00000004500 | ENSPPYP00000013217 | CD3E isoform 2. | GRB2 related adaptor protein 2. | 0.525 |
| CD3E | LAT | ENSPPYP00000004500 | ENSPPYP00000008163 | CD3E isoform 2. | LAT isoform 2. | 0.996 |
| CD3E | LCP2 | ENSPPYP00000004500 | ENSPPYP00000017943 | CD3E isoform 2. | LCP2 isoform 3. | 0.603 |
| CD3E | PIK3R1 | ENSPPYP00000004500 | ENSPPYP00000017341 | CD3E isoform 2. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.552 |
| CD3E | PLCG1 | ENSPPYP00000004500 | ENSPPYP00000012298 | CD3E isoform 2. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.416 |
| CD3E | SYK | ENSPPYP00000004500 | ENSPPYP00000021701 | CD3E isoform 2. | Tyrosine-protein kinase. | 0.950 |
| CD3E | ZAP70 | ENSPPYP00000004500 | ENSPPYP00000013469 | CD3E isoform 2. | Tyrosine-protein kinase. | 0.998 |
| GRAP2 | CD3E | ENSPPYP00000013217 | ENSPPYP00000004500 | GRB2 related adaptor protein 2. | CD3E isoform 2. | 0.525 |
| GRAP2 | GRB2 | ENSPPYP00000013217 | ENSPPYP00000009686 | GRB2 related adaptor protein 2. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.693 |
| GRAP2 | LAT | ENSPPYP00000013217 | ENSPPYP00000008163 | GRB2 related adaptor protein 2. | LAT isoform 2. | 0.998 |
| GRAP2 | LAT2 | ENSPPYP00000013217 | ENSPPYP00000019604 | GRB2 related adaptor protein 2. | Linker for activation of T cells family member 2. | 0.519 |
| GRAP2 | LCP2 | ENSPPYP00000013217 | ENSPPYP00000017943 | GRB2 related adaptor protein 2. | LCP2 isoform 3. | 0.999 |
| GRAP2 | PIK3R1 | ENSPPYP00000013217 | ENSPPYP00000017341 | GRB2 related adaptor protein 2. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.589 |
| GRAP2 | PLCG1 | ENSPPYP00000013217 | ENSPPYP00000012298 | GRB2 related adaptor protein 2. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.889 |
| GRAP2 | PLCG2 | ENSPPYP00000013217 | ENSPPYP00000008564 | GRB2 related adaptor protein 2. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.910 |
| GRAP2 | SYK | ENSPPYP00000013217 | ENSPPYP00000021701 | GRB2 related adaptor protein 2. | Tyrosine-protein kinase. | 0.649 |
| GRAP2 | ZAP70 | ENSPPYP00000013217 | ENSPPYP00000013469 | GRB2 related adaptor protein 2. | Tyrosine-protein kinase. | 0.774 |
| GRB2 | GRAP2 | ENSPPYP00000009686 | ENSPPYP00000013217 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | GRB2 related adaptor protein 2. | 0.693 |
| GRB2 | LAT | ENSPPYP00000009686 | ENSPPYP00000008163 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | LAT isoform 2. | 0.997 |
| GRB2 | LAT2 | ENSPPYP00000009686 | ENSPPYP00000019604 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Linker for activation of T cells family member 2. | 0.984 |
