| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIM2 | CASP1 | ENSPPYP00000000773 | ENSPPYP00000004375 | Absent in melanoma 2. | CASP1 isoform 4; Belongs to the peptidase C14A family. | 0.993 |
| AIM2 | CASP8 | ENSPPYP00000000773 | ENSPPYP00000014605 | Absent in melanoma 2. | CASP8 isoform 1; Belongs to the peptidase C14A family. | 0.934 |
| AIM2 | IL1B | ENSPPYP00000000773 | ENSPPYP00000013573 | Absent in melanoma 2. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.521 |
| AIM2 | MEFV | ENSPPYP00000000773 | ENSPPYP00000007958 | Absent in melanoma 2. | MEFV isoform 4. | 0.809 |
| AIM2 | NLRC4 | ENSPPYP00000000773 | ENSPPYP00000013968 | Absent in melanoma 2. | NLRC4 isoform 1. | 0.849 |
| AIM2 | NLRP1 | ENSPPYP00000000773 | ENSPPYP00000008863 | Absent in melanoma 2. | NLR family pyrin domain containing 1. | 0.907 |
| AIM2 | NLRP12 | ENSPPYP00000000773 | ENSPPYP00000011607 | Absent in melanoma 2. | NLRP12 isoform 1. | 0.484 |
| AIM2 | NLRP3 | ENSPPYP00000000773 | ENSPPYP00000000034 | Absent in melanoma 2. | NLRP3 isoform 2. | 0.583 |
| AIM2 | NLRP7 | ENSPPYP00000000773 | ENSPPYP00000011653 | Absent in melanoma 2. | NLRP7 isoform 8. | 0.523 |
| AIM2 | PYCARD | ENSPPYP00000000773 | ENSPPYP00000008260 | Absent in melanoma 2. | PYD and CARD domain containing. | 0.998 |
| CASP1 | AIM2 | ENSPPYP00000004375 | ENSPPYP00000000773 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Absent in melanoma 2. | 0.993 |
| CASP1 | CASP8 | ENSPPYP00000004375 | ENSPPYP00000014605 | CASP1 isoform 4; Belongs to the peptidase C14A family. | CASP8 isoform 1; Belongs to the peptidase C14A family. | 0.971 |
| CASP1 | IL1B | ENSPPYP00000004375 | ENSPPYP00000013573 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.996 |
| CASP1 | MEFV | ENSPPYP00000004375 | ENSPPYP00000007958 | CASP1 isoform 4; Belongs to the peptidase C14A family. | MEFV isoform 4. | 0.992 |
| CASP1 | NLRC4 | ENSPPYP00000004375 | ENSPPYP00000013968 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRC4 isoform 1. | 0.996 |
| CASP1 | NLRP1 | ENSPPYP00000004375 | ENSPPYP00000008863 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLR family pyrin domain containing 1. | 0.976 |
| CASP1 | NLRP12 | ENSPPYP00000004375 | ENSPPYP00000011607 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRP12 isoform 1. | 0.607 |
| CASP1 | NLRP3 | ENSPPYP00000004375 | ENSPPYP00000000034 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRP3 isoform 2. | 0.951 |
| CASP1 | NLRP7 | ENSPPYP00000004375 | ENSPPYP00000011653 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRP7 isoform 8. | 0.613 |
| CASP1 | PYCARD | ENSPPYP00000004375 | ENSPPYP00000008260 | CASP1 isoform 4; Belongs to the peptidase C14A family. | PYD and CARD domain containing. | 0.999 |
