STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPPYP00000008314Liver carboxylesterase 1-like isoform X1. (246 aa)    
Predicted Functional Partners:
CES2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
  
  
0.969
CYP3A4
Cytochrome P450 family 3 subfamily A member 4.
   
 
 0.935
UGT2B7
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.921
MPO
Myeloperoxidase.
   
 0.917
UGT2A3
UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity).
   
 
 0.915
UGT2B4
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.915
CYP2E1
CYP2E1 isoform 1; Belongs to the cytochrome P450 family.
   
 0.913
NAT2
Arylamine N-acetyltransferase 2; Belongs to the arylamine N-acetyltransferase family.
    
 0.905
CR201_G0048269
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.904
CR201_G0048259
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.904
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.