Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CR201_G0014562Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (523 aa)    
Predicted Functional Partners:
ESD
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
    
 
 0.637
QSOX1
Sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
      
 0.601
SIAE
Sialate O-acetylesterase; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.
      
 0.554
WDR43
WDR43 isoform 1.
   
 0.541
TGM4
TGM4 isoform 1.
   
  
 0.537
UTP4
UTP4 small subunit processome component.
   
 0.514
NRXN2
NRXN2 isoform 3.
   
 0.504
NRXN3
NRXN3 isoform 6.
   
 0.504
NRXN1
NRXN1 isoform 9.
   
 0.504
HAGH
HAGH isoform 2.
      
 0.490
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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