| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CPSF1 | CPSF2 | ENSPPYP00000021278 | ENSPPYP00000023779 | CPSF1 isoform 3. | Cleavage and polyadenylation specificity factor subunit 2. | 0.999 |
| CPSF1 | CPSF3 | ENSPPYP00000021278 | ENSPPYP00000014140 | CPSF1 isoform 3. | CPSF3 isoform 1. | 0.999 |
| CPSF1 | CPSF4 | ENSPPYP00000021278 | ENSPPYP00000019472 | CPSF1 isoform 3. | CPSF4 isoform 5. | 0.998 |
| CPSF1 | CPSF6 | ENSPPYP00000021278 | ENSPPYP00000005418 | CPSF1 isoform 3. | Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.889 |
| CPSF1 | CPSF7 | ENSPPYP00000021278 | ENSPPYP00000003678 | CPSF1 isoform 3. | CPSF7 isoform 16. | 0.873 |
| CPSF1 | CSTF1 | ENSPPYP00000021278 | ENSPPYP00000024472 | CPSF1 isoform 3. | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 0.954 |
| CPSF1 | CSTF2T | ENSPPYP00000021278 | ENSPPYP00000002831 | CPSF1 isoform 3. | Cleavage stimulation factor subunit 2 tau variant. | 0.943 |
| CPSF1 | FIP1L1 | ENSPPYP00000021278 | ENSPPYP00000016499 | CPSF1 isoform 3. | Pre-mRNA 3'-end-processing factor FIP1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity). | 0.998 |
| CPSF1 | NUDT21 | ENSPPYP00000021278 | ENSPPYP00000008319 | CPSF1 isoform 3. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.926 |
| CPSF1 | PCF11 | ENSPPYP00000021278 | ENSPPYP00000004264 | CPSF1 isoform 3. | PCF11 cleavage and polyadenylation factor subunit. | 0.969 |
| CPSF2 | CPSF1 | ENSPPYP00000023779 | ENSPPYP00000021278 | Cleavage and polyadenylation specificity factor subunit 2. | CPSF1 isoform 3. | 0.999 |
| CPSF2 | CPSF3 | ENSPPYP00000023779 | ENSPPYP00000014140 | Cleavage and polyadenylation specificity factor subunit 2. | CPSF3 isoform 1. | 0.999 |
| CPSF2 | CPSF4 | ENSPPYP00000023779 | ENSPPYP00000019472 | Cleavage and polyadenylation specificity factor subunit 2. | CPSF4 isoform 5. | 0.994 |
| CPSF2 | CPSF6 | ENSPPYP00000023779 | ENSPPYP00000005418 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.950 |
| CPSF2 | CPSF7 | ENSPPYP00000023779 | ENSPPYP00000003678 | Cleavage and polyadenylation specificity factor subunit 2. | CPSF7 isoform 16. | 0.951 |
| CPSF2 | CSTF1 | ENSPPYP00000023779 | ENSPPYP00000024472 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 0.987 |
| CPSF2 | CSTF2T | ENSPPYP00000023779 | ENSPPYP00000002831 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage stimulation factor subunit 2 tau variant. | 0.956 |
| CPSF2 | FIP1L1 | ENSPPYP00000023779 | ENSPPYP00000016499 | Cleavage and polyadenylation specificity factor subunit 2. | Pre-mRNA 3'-end-processing factor FIP1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity). | 0.998 |
| CPSF2 | NUDT21 | ENSPPYP00000023779 | ENSPPYP00000008319 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.954 |
| CPSF2 | PCF11 | ENSPPYP00000023779 | ENSPPYP00000004264 | Cleavage and polyadenylation specificity factor subunit 2. | PCF11 cleavage and polyadenylation factor subunit. | 0.989 |
