| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDA | CES1 | ENSPPYP00000002054 | ENSPPYP00000008315 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.902 |
| CDA | CES2 | ENSPPYP00000002054 | ENSPPYP00000008400 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.903 |
| CDA | ENSPPYP00000008314 | ENSPPYP00000002054 | ENSPPYP00000008314 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Liver carboxylesterase 1-like isoform X1. | 0.902 |
| CES1 | CDA | ENSPPYP00000008315 | ENSPPYP00000002054 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.902 |
| CES1 | CES2 | ENSPPYP00000008315 | ENSPPYP00000008400 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.947 |
| CES1 | CES3 | ENSPPYP00000008315 | ENSPPYP00000008401 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Carboxylesterase 3; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.400 |
| CES1 | CYP3A4 | ENSPPYP00000008315 | ENSPPYP00000019486 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450 family 3 subfamily A member 4. | 0.922 |
| CES1 | ENSPPYP00000008314 | ENSPPYP00000008315 | ENSPPYP00000008314 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Liver carboxylesterase 1-like isoform X1. | 0.901 |
| CES1 | GUSB | ENSPPYP00000008315 | ENSPPYP00000019644 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | 0.931 |
| CES1 | UGT1A3 | ENSPPYP00000008315 | ENSPPYP00000014864 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.674 |
| CES1 | UGT2A3 | ENSPPYP00000008315 | ENSPPYP00000016512 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). | 0.680 |
| CES1 | UGT2B4 | ENSPPYP00000008315 | ENSPPYP00000016516 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.681 |
| CES1 | UGT2B7 | ENSPPYP00000008315 | ENSPPYP00000016513 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.697 |
| CES2 | CDA | ENSPPYP00000008400 | ENSPPYP00000002054 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.903 |
| CES2 | CES1 | ENSPPYP00000008400 | ENSPPYP00000008315 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.947 |
| CES2 | CES3 | ENSPPYP00000008400 | ENSPPYP00000008401 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Carboxylesterase 3; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.706 |
| CES2 | CYP3A4 | ENSPPYP00000008400 | ENSPPYP00000019486 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450 family 3 subfamily A member 4. | 0.921 |
| CES2 | ENSPPYP00000008314 | ENSPPYP00000008400 | ENSPPYP00000008314 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Liver carboxylesterase 1-like isoform X1. | 0.947 |
| CES2 | GUSB | ENSPPYP00000008400 | ENSPPYP00000019644 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | 0.906 |
| CES2 | UGT1A3 | ENSPPYP00000008400 | ENSPPYP00000014864 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.686 |
