ZFHX3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN3	ATXN7	ENSPPYP00000006907	ENSPPYP00000015372	ATXN3 isoform 7.	ATXN7 isoform 1.	0.788
ATXN3	CEL	ENSPPYP00000006907	ENSPPYP00000022270	ATXN3 isoform 7.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.583
ATXN3	MED12	ENSPPYP00000006907	ENSPPYP00000022889	ATXN3 isoform 7.	MED12 isoform 3.	0.608
ATXN3	PAXIP1	ENSPPYP00000006907	ENSPPYP00000020416	ATXN3 isoform 7.	PAX interacting protein 1.	0.824
ATXN3	RUNX1	ENSPPYP00000006907	ENSPPYP00000012719	ATXN3 isoform 7.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.447
ATXN3	RUNX2	ENSPPYP00000006907	ENSPPYP00000018641	ATXN3 isoform 7.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.527
ATXN3	ZFHX3	ENSPPYP00000006907	ENSPPYP00000008484	ATXN3 isoform 7.	ZFHX3 isoform 7.	0.738
ATXN7	ATXN3	ENSPPYP00000015372	ENSPPYP00000006907	ATXN7 isoform 1.	ATXN3 isoform 7.	0.788
ATXN7	CEL	ENSPPYP00000015372	ENSPPYP00000022270	ATXN7 isoform 1.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.825
ATXN7	MED12	ENSPPYP00000015372	ENSPPYP00000022889	ATXN7 isoform 1.	MED12 isoform 3.	0.805
ATXN7	PAXIP1	ENSPPYP00000015372	ENSPPYP00000020416	ATXN7 isoform 1.	PAX interacting protein 1.	0.749
ATXN7	RUNX1	ENSPPYP00000015372	ENSPPYP00000012719	ATXN7 isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.511
ATXN7	RUNX2	ENSPPYP00000015372	ENSPPYP00000018641	ATXN7 isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.511
ATXN7	RUNX3	ENSPPYP00000015372	ENSPPYP00000001981	ATXN7 isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.511
ATXN7	ZFHX3	ENSPPYP00000015372	ENSPPYP00000008484	ATXN7 isoform 1.	ZFHX3 isoform 7.	0.841
CEL	ATXN3	ENSPPYP00000022270	ENSPPYP00000006907	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	ATXN3 isoform 7.	0.583
CEL	ATXN7	ENSPPYP00000022270	ENSPPYP00000015372	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	ATXN7 isoform 1.	0.825
CEL	MED12	ENSPPYP00000022270	ENSPPYP00000022889	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	MED12 isoform 3.	0.621
CEL	PAXIP1	ENSPPYP00000022270	ENSPPYP00000020416	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	PAX interacting protein 1.	0.792
CEL	RUNX1	ENSPPYP00000022270	ENSPPYP00000012719	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.549