AP1G1 protein (Pongo abelii) - STRING interaction network

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AP1G1

AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). (822 aa)

Predicted Functional Partners:

AP1B1

0.999

AP1S1

0.996

AP1S2

0.993

AP1M1

0.986

AP1S3

0.970

GAK

0.954

AP2B1

0.952

RABEP1

0.927

ARF1

0.926

AP2M1

0.926

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1B1	AP1G1	ENSPPYP00000013038	ENSPPYP00000008496	AP complex subunit beta.	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	0.999
AP1B1	AP1M1	ENSPPYP00000013038	ENSPPYP00000010856	AP complex subunit beta.	Protein FAM32A; May induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli; Belongs to the FAM32 family.	0.978
AP1B1	AP1S1	ENSPPYP00000013038	ENSPPYP00000019550	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.997
AP1B1	AP1S2	ENSPPYP00000013038	ENSPPYP00000022541	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.996
AP1B1	AP1S3	ENSPPYP00000013038	ENSPPYP00000014781	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.957
AP1B1	AP2B1	ENSPPYP00000013038	ENSPPYP00000009206	AP complex subunit beta.	AP complex subunit beta.	0.594
AP1B1	AP2M1	ENSPPYP00000013038	ENSPPYP00000016043	AP complex subunit beta.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.975
AP1B1	ARF1	ENSPPYP00000013038	ENSPPYP00000000146	AP complex subunit beta.	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	0.954
AP1B1	GAK	ENSPPYP00000013038	ENSPPYP00000016219	AP complex subunit beta.	GAK isoform 7.	0.962
AP1G1	AP1B1	ENSPPYP00000008496	ENSPPYP00000013038	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP complex subunit beta.	0.999
AP1G1	AP1M1	ENSPPYP00000008496	ENSPPYP00000010856	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	Protein FAM32A; May induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli; Belongs to the FAM32 family.	0.986
AP1G1	AP1S1	ENSPPYP00000008496	ENSPPYP00000019550	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.996
AP1G1	AP1S2	ENSPPYP00000008496	ENSPPYP00000022541	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.993
AP1G1	AP1S3	ENSPPYP00000008496	ENSPPYP00000014781	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.970
AP1G1	AP2B1	ENSPPYP00000008496	ENSPPYP00000009206	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP complex subunit beta.	0.952
AP1G1	AP2M1	ENSPPYP00000008496	ENSPPYP00000016043	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.926
AP1G1	ARF1	ENSPPYP00000008496	ENSPPYP00000000146	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	0.926
AP1G1	GAK	ENSPPYP00000008496	ENSPPYP00000016219	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	GAK isoform 7.	0.954
AP1G1	RABEP1	ENSPPYP00000008496	ENSPPYP00000008856	AP-1 complex subunit gamma-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).	Rabaptin, RAB GTPase binding effector protein 1.	0.927
AP1M1	AP1B1	ENSPPYP00000010856	ENSPPYP00000013038	Protein FAM32A; May induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli; Belongs to the FAM32 family.	AP complex subunit beta.	0.978

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