TUBB3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000004309	LOC100434822	ENSPPYP00000004309	ENSPPYP00000022337	annotation not available	TUBA3C isoform 1.	0.689
ENSPPYP00000004309	MAPRE3	ENSPPYP00000004309	ENSPPYP00000014037	annotation not available	Microtubule associated protein RP/EB family member 3.	0.678
ENSPPYP00000004309	MAPT	ENSPPYP00000004309	ENSPPYP00000009325	annotation not available	Microtubule-associated protein.	0.751
ENSPPYP00000004309	TUBA1C	ENSPPYP00000004309	ENSPPYP00000024164	annotation not available	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.969
ENSPPYP00000004309	TUBA4A	ENSPPYP00000004309	ENSPPYP00000014752	annotation not available	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.971
ENSPPYP00000004309	TUBA8	ENSPPYP00000004309	ENSPPYP00000024156	annotation not available	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.854
ENSPPYP00000004309	TUBB3	ENSPPYP00000004309	ENSPPYP00000008654	annotation not available	T0170152 isoform 1; Belongs to the tubulin family.	0.878
GJA1	LOC100434822	ENSPPYP00000019004	ENSPPYP00000022337	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	TUBA3C isoform 1.	0.900
GJA1	TUBA1B	ENSPPYP00000019004	ENSPPYP00000024744	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.900
GJA1	TUBA1C	ENSPPYP00000019004	ENSPPYP00000024164	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.900
GJA1	TUBA4A	ENSPPYP00000019004	ENSPPYP00000014752	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.900
GJA1	TUBA8	ENSPPYP00000019004	ENSPPYP00000024156	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.900
GJA1	TUBAL3	ENSPPYP00000019004	ENSPPYP00000002379	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.900
GJA1	TUBB3	ENSPPYP00000019004	ENSPPYP00000008654	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	T0170152 isoform 1; Belongs to the tubulin family.	0.903
LOC100434822	ENSPPYP00000004309	ENSPPYP00000022337	ENSPPYP00000004309	TUBA3C isoform 1.	annotation not available	0.689
LOC100434822	GJA1	ENSPPYP00000022337	ENSPPYP00000019004	TUBA3C isoform 1.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.900
LOC100434822	MAPRE3	ENSPPYP00000022337	ENSPPYP00000014037	TUBA3C isoform 1.	Microtubule associated protein RP/EB family member 3.	0.520
LOC100434822	MAPT	ENSPPYP00000022337	ENSPPYP00000009325	TUBA3C isoform 1.	Microtubule-associated protein.	0.953
LOC100434822	TUBA1B	ENSPPYP00000022337	ENSPPYP00000024744	TUBA3C isoform 1.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.790
LOC100434822	TUBA1C	ENSPPYP00000022337	ENSPPYP00000024164	TUBA3C isoform 1.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.823