HSBP1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG101	ATG13	ENSPPYP00000005179	ENSPPYP00000003811	ATG101 isoform 1.	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).	0.999
ATG101	HSBP1	ENSPPYP00000005179	ENSPPYP00000008675	ATG101 isoform 1.	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	0.702
ATG101	WASHC3	ENSPPYP00000005179	ENSPPYP00000005568	ATG101 isoform 1.	WASHC3 isoform 2.	0.532
ATG13	ATG101	ENSPPYP00000003811	ENSPPYP00000005179	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).	ATG101 isoform 1.	0.999
ATG13	HSBP1	ENSPPYP00000003811	ENSPPYP00000008675	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	0.636
ATG13	WASHC3	ENSPPYP00000003811	ENSPPYP00000005568	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).	WASHC3 isoform 2.	0.499
BRK1	HSBP1	ENSPPYP00000015277	ENSPPYP00000008675	BRK1 isoform 1.	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	0.675
BRK1	WASHC3	ENSPPYP00000015277	ENSPPYP00000005568	BRK1 isoform 1.	WASHC3 isoform 2.	0.788
HSBP1	ATG101	ENSPPYP00000008675	ENSPPYP00000005179	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	ATG101 isoform 1.	0.702
HSBP1	ATG13	ENSPPYP00000008675	ENSPPYP00000003811	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation (By similarity).	0.636
HSBP1	BRK1	ENSPPYP00000008675	ENSPPYP00000015277	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	BRK1 isoform 1.	0.675
HSBP1	HSF1	ENSPPYP00000008675	ENSPPYP00000021274	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	HSF1 isoform 2.	0.855
HSBP1	HSF2	ENSPPYP00000008675	ENSPPYP00000019006	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	Heat shock transcription factor 2.	0.624
HSBP1	HSF4	ENSPPYP00000008675	ENSPPYP00000008407	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	HSF4 isoform 10.	0.679
HSBP1	LOC100447565	ENSPPYP00000008675	ENSPPYP00000018756	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	SMS isoform 1.	0.717
HSBP1	SMS	ENSPPYP00000008675	ENSPPYP00000022584	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	Spermine synthase isoform X2.	0.717
HSBP1	STOML2	ENSPPYP00000008675	ENSPPYP00000021405	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	STOML2 isoform 3.	0.787
HSBP1	WASHC3	ENSPPYP00000008675	ENSPPYP00000005568	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	WASHC3 isoform 2.	0.836
HSF1	HSBP1	ENSPPYP00000021274	ENSPPYP00000008675	HSF1 isoform 2.	Heat shock factor-binding protein 1; Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity).	0.855
HSF1	HSF2	ENSPPYP00000021274	ENSPPYP00000019006	HSF1 isoform 2.	Heat shock transcription factor 2.	0.916