CR201_G0047047 protein (Pongo abelii) - STRING interaction network

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Score

CR201_G0047047

SMG1 isoform 2. (163 aa)

Predicted Functional Partners:

SMG1

0.916

SMG9

0.893

SMG8

0.892

SMG7

0.885

RPTOR

0.881

RICTOR

0.880

MLST8

0.871

MAPKAP1

0.871

UPF2

0.835

UPF1

0.824

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0047047	MAPKAP1	ENSPPYP00000008730	ENSPPYP00000021975	SMG1 isoform 2.	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	0.871
CR201_G0047047	MLST8	ENSPPYP00000008730	ENSPPYP00000007913	SMG1 isoform 2.	MTOR associated protein, LST8 homolog.	0.871
CR201_G0047047	RICTOR	ENSPPYP00000008730	ENSPPYP00000017219	SMG1 isoform 2.	RICTOR isoform 1.	0.880
CR201_G0047047	RPTOR	ENSPPYP00000008730	ENSPPYP00000024617	SMG1 isoform 2.	RPTOR isoform 4.	0.881
CR201_G0047047	SMG1	ENSPPYP00000008730	ENSPPYP00000008072	SMG1 isoform 2.	SMG1 isoform 8; Belongs to the PI3/PI4-kinase family.	0.916
CR201_G0047047	SMG7	ENSPPYP00000008730	ENSPPYP00000000485	SMG1 isoform 2.	SMG7 nonsense mediated mRNA decay factor.	0.885
CR201_G0047047	SMG8	ENSPPYP00000008730	ENSPPYP00000009242	SMG1 isoform 2.	Protein SMG8.	0.892
CR201_G0047047	SMG9	ENSPPYP00000008730	ENSPPYP00000023744	SMG1 isoform 2.	SMG9 nonsense mediated mRNA decay factor.	0.893
CR201_G0047047	UPF1	ENSPPYP00000008730	ENSPPYP00000010923	SMG1 isoform 2.	UPF1 isoform 2.	0.824
CR201_G0047047	UPF2	ENSPPYP00000008730	ENSPPYP00000002423	SMG1 isoform 2.	UPF2 isoform 1.	0.835
MAPKAP1	CR201_G0047047	ENSPPYP00000021975	ENSPPYP00000008730	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	SMG1 isoform 2.	0.871
MAPKAP1	MLST8	ENSPPYP00000021975	ENSPPYP00000007913	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	MTOR associated protein, LST8 homolog.	0.999
MAPKAP1	RICTOR	ENSPPYP00000021975	ENSPPYP00000017219	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	RICTOR isoform 1.	0.999
MAPKAP1	RPTOR	ENSPPYP00000021975	ENSPPYP00000024617	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	RPTOR isoform 4.	0.883
MAPKAP1	SMG1	ENSPPYP00000021975	ENSPPYP00000008072	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	SMG1 isoform 8; Belongs to the PI3/PI4-kinase family.	0.871
MLST8	CR201_G0047047	ENSPPYP00000007913	ENSPPYP00000008730	MTOR associated protein, LST8 homolog.	SMG1 isoform 2.	0.871
MLST8	MAPKAP1	ENSPPYP00000007913	ENSPPYP00000021975	MTOR associated protein, LST8 homolog.	Target of rapamycin complex 2 subunit MAPKAP1; Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the [...]	0.999
MLST8	RICTOR	ENSPPYP00000007913	ENSPPYP00000017219	MTOR associated protein, LST8 homolog.	RICTOR isoform 1.	0.999
MLST8	RPTOR	ENSPPYP00000007913	ENSPPYP00000024617	MTOR associated protein, LST8 homolog.	RPTOR isoform 4.	0.999
MLST8	SMG1	ENSPPYP00000007913	ENSPPYP00000008072	MTOR associated protein, LST8 homolog.	SMG1 isoform 8; Belongs to the PI3/PI4-kinase family.	0.871