node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD27 | SGSM2 | ENSPPYP00000010994 | ENSPPYP00000008780 | Ankyrin repeat domain-containing protein 27; May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics. May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (By similarity). Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7. Involved in the regulation of neurite growth; the fun [...] | SGSM2 isoform 3. | 0.513 |
RAB11A | RAB4A | ENSPPYP00000007454 | ENSPPYP00000000130 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | RAB4A, member RAS oncogene family. | 0.473 |
RAB11A | RAB9B | ENSPPYP00000007454 | ENSPPYP00000023047 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | 0.437 |
RAB11A | RABGEF1 | ENSPPYP00000007454 | ENSPPYP00000019637 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | RABGEF1 isoform 2. | 0.412 |
RAB11A | SGSM2 | ENSPPYP00000007454 | ENSPPYP00000008780 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | SGSM2 isoform 3. | 0.524 |
RAB11A | SGSM3 | ENSPPYP00000007454 | ENSPPYP00000013223 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | SGSM3 isoform 1. | 0.564 |
RAB3A | SGSM2 | ENSPPYP00000010905 | ENSPPYP00000008780 | Ras-related protein Rab-3A. | SGSM2 isoform 3. | 0.530 |
RAB3A | SGSM3 | ENSPPYP00000010905 | ENSPPYP00000013223 | Ras-related protein Rab-3A. | SGSM3 isoform 1. | 0.557 |
RAB4A | RAB11A | ENSPPYP00000000130 | ENSPPYP00000007454 | RAB4A, member RAS oncogene family. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.473 |
RAB4A | RAB9B | ENSPPYP00000000130 | ENSPPYP00000023047 | RAB4A, member RAS oncogene family. | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | 0.428 |
RAB4A | RABGEF1 | ENSPPYP00000000130 | ENSPPYP00000019637 | RAB4A, member RAS oncogene family. | RABGEF1 isoform 2. | 0.632 |
RAB4A | SGSM2 | ENSPPYP00000000130 | ENSPPYP00000008780 | RAB4A, member RAS oncogene family. | SGSM2 isoform 3. | 0.570 |
RAB4A | SGSM3 | ENSPPYP00000000130 | ENSPPYP00000013223 | RAB4A, member RAS oncogene family. | SGSM3 isoform 1. | 0.618 |
RAB9B | RAB11A | ENSPPYP00000023047 | ENSPPYP00000007454 | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.437 |
RAB9B | RAB4A | ENSPPYP00000023047 | ENSPPYP00000000130 | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | RAB4A, member RAS oncogene family. | 0.428 |
RAB9B | RABGEF1 | ENSPPYP00000023047 | ENSPPYP00000019637 | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | RABGEF1 isoform 2. | 0.460 |
RAB9B | SGSM2 | ENSPPYP00000023047 | ENSPPYP00000008780 | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | SGSM2 isoform 3. | 0.521 |
RABGEF1 | RAB11A | ENSPPYP00000019637 | ENSPPYP00000007454 | RABGEF1 isoform 2. | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] | 0.412 |
RABGEF1 | RAB4A | ENSPPYP00000019637 | ENSPPYP00000000130 | RABGEF1 isoform 2. | RAB4A, member RAS oncogene family. | 0.632 |
RABGEF1 | RAB9B | ENSPPYP00000019637 | ENSPPYP00000023047 | RABGEF1 isoform 2. | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. | 0.460 |