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ASPA protein (Pongo abelii) - STRING interaction network
"ASPA" - Aspartoacylase in Pongo abelii
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ASPAAspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids (By similarity) (313 aa)    
Predicted Functional Partners:
RIMKLB
Ribosomal modification protein rimK-like family member B (307 aa)
         
  0.924
RIMKLA
Ribosomal modification protein rimK-like family member A (350 aa)
         
  0.924
FOLH1
Folate hydrolase (prostate-specific membrane antigen) 1 (750 aa)
     
 
  0.908
NAT8L
Uncharacterized protein; N-acetyltransferase 8-like (GCN5-related, putative) (126 aa)
     
 
  0.908
GOT2
Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity) (430 aa)
         
  0.904
ASS1
Argininosuccinate synthase (359 aa)
     
 
  0.903
CAD
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (2225 aa)
         
  0.902
ASNS
Pongo abelii asparagine synthetase (glutamine-hydrolyzing) (ASNS), mRNA (561 aa)
         
  0.900
ADSSL1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP (457 aa)
         
    0.900
ADSS
Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP (456 aa)
         
    0.900
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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