Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADRB2 | ARRB1 | ENSPPYP00000017819 | ENSPPYP00000004214 | Adrenoceptor beta 2. | ARRB1 isoform 2. | 0.985 |
| ADRB2 | ARRB2 | ENSPPYP00000017819 | ENSPPYP00000008826 | Adrenoceptor beta 2. | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.989 |
| ADRB2 | GRK2 | ENSPPYP00000017819 | ENSPPYP00000003477 | Adrenoceptor beta 2. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.863 |
| ADRB2 | OPRM1 | ENSPPYP00000017819 | ENSPPYP00000024191 | Adrenoceptor beta 2. | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. | 0.613 |
| ADRB2 | SMO | ENSPPYP00000017819 | ENSPPYP00000020186 | Adrenoceptor beta 2. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.480 |
| ARRB1 | ADRB2 | ENSPPYP00000004214 | ENSPPYP00000017819 | ARRB1 isoform 2. | Adrenoceptor beta 2. | 0.985 |
| ARRB1 | ARRB2 | ENSPPYP00000004214 | ENSPPYP00000008826 | ARRB1 isoform 2. | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.982 |
| ARRB1 | DRD2 | ENSPPYP00000004214 | ENSPPYP00000004451 | ARRB1 isoform 2. | DRD2 isoform 2; Belongs to the G-protein coupled receptor 1 family. | 0.966 |
| ARRB1 | DVL2 | ENSPPYP00000004214 | ENSPPYP00000008887 | ARRB1 isoform 2. | DVL2 isoform 1. | 0.765 |
| ARRB1 | GRK2 | ENSPPYP00000004214 | ENSPPYP00000003477 | ARRB1 isoform 2. | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.976 |
| ARRB1 | MAP2K4 | ENSPPYP00000004214 | ENSPPYP00000023632 | ARRB1 isoform 2. | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | 0.940 |
| ARRB1 | MAPK1 | ENSPPYP00000004214 | ENSPPYP00000023664 | ARRB1 isoform 2. | Mitogen-activated protein kinase 1 isoform X1. | 0.970 |
| ARRB1 | MAPK3 | ENSPPYP00000004214 | ENSPPYP00000008184 | ARRB1 isoform 2. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.978 |
| ARRB1 | OPRM1 | ENSPPYP00000004214 | ENSPPYP00000024191 | ARRB1 isoform 2. | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. | 0.969 |
| ARRB1 | SMO | ENSPPYP00000004214 | ENSPPYP00000020186 | ARRB1 isoform 2. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.982 |
| ARRB2 | ADRB2 | ENSPPYP00000008826 | ENSPPYP00000017819 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Adrenoceptor beta 2. | 0.989 |
| ARRB2 | ARRB1 | ENSPPYP00000008826 | ENSPPYP00000004214 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | ARRB1 isoform 2. | 0.982 |
| ARRB2 | DRD2 | ENSPPYP00000008826 | ENSPPYP00000004451 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | DRD2 isoform 2; Belongs to the G-protein coupled receptor 1 family. | 0.987 |
| ARRB2 | DVL2 | ENSPPYP00000008826 | ENSPPYP00000008887 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | DVL2 isoform 1. | 0.965 |
| ARRB2 | GRK2 | ENSPPYP00000008826 | ENSPPYP00000003477 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. | 0.977 |
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