| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDK5 | NDE1 | ENSPPYP00000020390 | ENSPPYP00000008062 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | NDE1 isoform 1. | 0.618 |
| CDK5 | NDEL1 | ENSPPYP00000020390 | ENSPPYP00000008952 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] | 0.842 |
| CENPF | NDE1 | ENSPPYP00000000228 | ENSPPYP00000008062 | CENPF isoform 1. | NDE1 isoform 1. | 0.951 |
| CENPF | NDEL1 | ENSPPYP00000000228 | ENSPPYP00000008952 | CENPF isoform 1. | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] | 0.908 |
| CENPF | NUDC | ENSPPYP00000000228 | ENSPPYP00000001931 | CENPF isoform 1. | Nuclear distribution C, dynein complex regulator. | 0.917 |
| CENPF | PAFAH1B1 | ENSPPYP00000000228 | ENSPPYP00000008783 | CENPF isoform 1. | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] | 0.849 |
| CENPF | PLK1 | ENSPPYP00000000228 | ENSPPYP00000008136 | CENPF isoform 1. | Serine/threonine-protein kinase PLK. | 0.983 |
| DIXDC1 | NDE1 | ENSPPYP00000004434 | ENSPPYP00000008062 | DIX domain containing 1. | NDE1 isoform 1. | 0.727 |
| DIXDC1 | NDEL1 | ENSPPYP00000004434 | ENSPPYP00000008952 | DIX domain containing 1. | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] | 0.918 |
| DYNC1I1 | DYNC1I2 | ENSPPYP00000019951 | ENSPPYP00000014432 | Dynein cytoplasmic 1 intermediate chain 1. | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | 0.993 |
| DYNC1I1 | NDE1 | ENSPPYP00000019951 | ENSPPYP00000008062 | Dynein cytoplasmic 1 intermediate chain 1. | NDE1 isoform 1. | 0.882 |
| DYNC1I1 | NDEL1 | ENSPPYP00000019951 | ENSPPYP00000008952 | Dynein cytoplasmic 1 intermediate chain 1. | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] | 0.921 |
| DYNC1I1 | NUDC | ENSPPYP00000019951 | ENSPPYP00000001931 | Dynein cytoplasmic 1 intermediate chain 1. | Nuclear distribution C, dynein complex regulator. | 0.644 |
| DYNC1I1 | PAFAH1B1 | ENSPPYP00000019951 | ENSPPYP00000008783 | Dynein cytoplasmic 1 intermediate chain 1. | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] | 0.983 |
| DYNC1I1 | PLK1 | ENSPPYP00000019951 | ENSPPYP00000008136 | Dynein cytoplasmic 1 intermediate chain 1. | Serine/threonine-protein kinase PLK. | 0.773 |
| DYNC1I2 | DYNC1I1 | ENSPPYP00000014432 | ENSPPYP00000019951 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | Dynein cytoplasmic 1 intermediate chain 1. | 0.993 |
| DYNC1I2 | NDE1 | ENSPPYP00000014432 | ENSPPYP00000008062 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | NDE1 isoform 1. | 0.915 |
| DYNC1I2 | NDEL1 | ENSPPYP00000014432 | ENSPPYP00000008952 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripe [...] | 0.882 |
| DYNC1I2 | NUDC | ENSPPYP00000014432 | ENSPPYP00000001931 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | Nuclear distribution C, dynein complex regulator. | 0.590 |
| DYNC1I2 | PAFAH1B1 | ENSPPYP00000014432 | ENSPPYP00000008783 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] | 0.987 |
