| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUL3 | FAF1 | ENSPPYP00000014786 | ENSPPYP00000024718 | CUL3 isoform 1; Belongs to the cullin family. | Fas associated factor 1. | 0.672 |
| CUL3 | KCTD10 | ENSPPYP00000014786 | ENSPPYP00000005629 | CUL3 isoform 1; Belongs to the cullin family. | Potassium channel tetramerization domain containing 10. | 0.948 |
| CUL3 | KCTD13 | ENSPPYP00000014786 | ENSPPYP00000008198 | CUL3 isoform 1; Belongs to the cullin family. | Potassium channel tetramerization domain containing 13. | 0.944 |
| CUL3 | RND2 | ENSPPYP00000014786 | ENSPPYP00000009405 | CUL3 isoform 1; Belongs to the cullin family. | RND2 isoform 1. | 0.403 |
| CUL3 | TNFAIP1 | ENSPPYP00000014786 | ENSPPYP00000009095 | CUL3 isoform 1; Belongs to the cullin family. | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity (By similarity). | 0.940 |
| CUL3 | UBXN1 | ENSPPYP00000014786 | ENSPPYP00000003643 | CUL3 isoform 1; Belongs to the cullin family. | UBXN1 isoform 1. | 0.578 |
| CUL3 | UBXN7 | ENSPPYP00000014786 | ENSPPYP00000016149 | CUL3 isoform 1; Belongs to the cullin family. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.953 |
| CUL3 | USP25 | ENSPPYP00000014786 | ENSPPYP00000012612 | CUL3 isoform 1; Belongs to the cullin family. | USP25 isoform 2; Belongs to the peptidase C19 family. | 0.612 |
| DNAJB1 | TNFAIP1 | ENSPPYP00000010811 | ENSPPYP00000009095 | DnaJ heat shock protein family (Hsp40) member B1. | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity (By similarity). | 0.736 |
| FAF1 | CUL3 | ENSPPYP00000024718 | ENSPPYP00000014786 | Fas associated factor 1. | CUL3 isoform 1; Belongs to the cullin family. | 0.672 |
| FAF1 | KCTD10 | ENSPPYP00000024718 | ENSPPYP00000005629 | Fas associated factor 1. | Potassium channel tetramerization domain containing 10. | 0.920 |
| FAF1 | KCTD13 | ENSPPYP00000024718 | ENSPPYP00000008198 | Fas associated factor 1. | Potassium channel tetramerization domain containing 13. | 0.920 |
| FAF1 | TNFAIP1 | ENSPPYP00000024718 | ENSPPYP00000009095 | Fas associated factor 1. | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity (By similarity). | 0.924 |
| FAF1 | UBXN1 | ENSPPYP00000024718 | ENSPPYP00000003643 | Fas associated factor 1. | UBXN1 isoform 1. | 0.969 |
| FAF1 | UBXN7 | ENSPPYP00000024718 | ENSPPYP00000016149 | Fas associated factor 1. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.970 |
| FLNC | KCTD13 | ENSPPYP00000020178 | ENSPPYP00000008198 | FLNC isoform 2. | Potassium channel tetramerization domain containing 13. | 0.784 |
| FLNC | TNFAIP1 | ENSPPYP00000020178 | ENSPPYP00000009095 | FLNC isoform 2. | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity (By similarity). | 0.745 |
| KCTD10 | CUL3 | ENSPPYP00000005629 | ENSPPYP00000014786 | Potassium channel tetramerization domain containing 10. | CUL3 isoform 1; Belongs to the cullin family. | 0.948 |
| KCTD10 | FAF1 | ENSPPYP00000005629 | ENSPPYP00000024718 | Potassium channel tetramerization domain containing 10. | Fas associated factor 1. | 0.920 |
| KCTD10 | KCTD13 | ENSPPYP00000005629 | ENSPPYP00000008198 | Potassium channel tetramerization domain containing 10. | Potassium channel tetramerization domain containing 13. | 0.935 |
