STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPN3EPN3 isoform 1. (638 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.985
ITSN2
ITSN2 isoform 3.
    
 0.972
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 0.965
EGFR
Receptor protein-tyrosine kinase.
    
 0.958
EPN1
EPN1 isoform 2.
    
0.930
ITSN1
ITSN1 isoform 4.
    
 0.917
PDGFRA
Platelet-derived growth factor receptor alpha.
    
  0.903
FGFR2
Fibroblast growth factor receptor.
    
  0.902
IGF1R
Tyrosine-protein kinase receptor.
    
  0.900
SNAP91
SNAP91 isoform 3.
   
 0.890
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.