STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSF2Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation; Belongs to the ATP-dependent AMP-binding enzyme family. (640 aa)    
Predicted Functional Partners:
HSDL2
Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.868
SOD2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.772
MRPL3
MRPL3 isoform 3; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.765
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.764
MRPL13
MRPL13 isoform 2; Belongs to the universal ribosomal protein uL13 family.
    
 
 0.762
MRPL24
Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.
    
   0.750
MRPL43
MRPL43 isoform 7.
    
   0.750
MRPL21
MRPL21 isoform 1.
    
   0.750
MRPL11
Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.
    
   0.750
MRPL17
39S ribosomal protein L17, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family.
    
   0.750
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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