| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BET1 | COPB2 | ENSPPYP00000024128 | ENSPPYP00000015835 | BET1 isoform 1. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | 0.894 |
| BET1 | NAPB | ENSPPYP00000024128 | ENSPPYP00000012031 | BET1 isoform 1. | NAPB isoform 4. | 0.914 |
| BET1 | NAPG | ENSPPYP00000024128 | ENSPPYP00000010101 | BET1 isoform 1. | NAPG isoform 3. | 0.926 |
| BET1 | NSF | ENSPPYP00000024128 | ENSPPYP00000009318 | BET1 isoform 1. | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. | 0.948 |
| BET1 | SCFD1 | ENSPPYP00000024128 | ENSPPYP00000006502 | BET1 isoform 1. | SCFD1 isoform 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.994 |
| BET1 | STX16 | ENSPPYP00000024128 | ENSPPYP00000012482 | BET1 isoform 1. | STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. | 0.656 |
| BET1 | STX18 | ENSPPYP00000024128 | ENSPPYP00000016308 | BET1 isoform 1. | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. | 0.858 |
| BET1 | STX5 | ENSPPYP00000024128 | ENSPPYP00000003630 | BET1 isoform 1. | STX5 isoform 1; Belongs to the syntaxin family. | 0.997 |
| BET1 | YKT6 | ENSPPYP00000024128 | ENSPPYP00000019721 | BET1 isoform 1. | YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. | 0.969 |
| COPB2 | BET1 | ENSPPYP00000015835 | ENSPPYP00000024128 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | BET1 isoform 1. | 0.894 |
| COPB2 | NAPB | ENSPPYP00000015835 | ENSPPYP00000012031 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | NAPB isoform 4. | 0.510 |
| COPB2 | NAPG | ENSPPYP00000015835 | ENSPPYP00000010101 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | NAPG isoform 3. | 0.537 |
| COPB2 | NSF | ENSPPYP00000015835 | ENSPPYP00000009318 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. | 0.918 |
| COPB2 | SCFD1 | ENSPPYP00000015835 | ENSPPYP00000006502 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | SCFD1 isoform 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.583 |
| COPB2 | STX18 | ENSPPYP00000015835 | ENSPPYP00000016308 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. | 0.844 |
| COPB2 | STX5 | ENSPPYP00000015835 | ENSPPYP00000003630 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | STX5 isoform 1; Belongs to the syntaxin family. | 0.502 |
| COPB2 | YKT6 | ENSPPYP00000015835 | ENSPPYP00000019721 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. | 0.738 |
| GABRA5 | NSF | ENSPPYP00000007113 | ENSPPYP00000009318 | Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. | 0.916 |
| NAPB | BET1 | ENSPPYP00000012031 | ENSPPYP00000024128 | NAPB isoform 4. | BET1 isoform 1. | 0.914 |
| NAPB | COPB2 | ENSPPYP00000012031 | ENSPPYP00000015835 | NAPB isoform 4. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] | 0.510 |
