DUSP3 protein (Pongo abelii) - STRING interaction network

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DUSP3

Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)

Predicted Functional Partners:

VRK3

0.959

MAPK1

0.955

MAPK3

0.951

PTPN7

0.946

MAPK9

0.937

MAPK12

0.935

MAPK14

0.935

MAPK13

0.935

MAPK8

0.933

MAPK10

0.930

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	MAPK1	ENSPPYP00000009390	ENSPPYP00000023664	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase 1 isoform X1.	0.955
DUSP3	MAPK10	ENSPPYP00000009390	ENSPPYP00000016644	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK12	ENSPPYP00000009390	ENSPPYP00000013363	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.935
DUSP3	MAPK13	ENSPPYP00000009390	ENSPPYP00000018501	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.935
DUSP3	MAPK14	ENSPPYP00000009390	ENSPPYP00000018500	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.935
DUSP3	MAPK3	ENSPPYP00000009390	ENSPPYP00000008184	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.951
DUSP3	MAPK8	ENSPPYP00000009390	ENSPPYP00000002621	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.933
DUSP3	MAPK9	ENSPPYP00000009390	ENSPPYP00000018050	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.937
DUSP3	PTPN7	ENSPPYP00000009390	ENSPPYP00000000393	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	PTPN7 isoform 3.	0.946
DUSP3	VRK3	ENSPPYP00000009390	ENSPPYP00000011500	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	VRK3 isoform 3.	0.959
MAPK1	DUSP3	ENSPPYP00000023664	ENSPPYP00000009390	Mitogen-activated protein kinase 1 isoform X1.	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.955
MAPK1	MAPK12	ENSPPYP00000023664	ENSPPYP00000013363	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase.	0.933
MAPK1	MAPK13	ENSPPYP00000023664	ENSPPYP00000018501	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase.	0.934
MAPK1	MAPK14	ENSPPYP00000023664	ENSPPYP00000018500	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase.	0.988
MAPK1	MAPK3	ENSPPYP00000023664	ENSPPYP00000008184	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.996
MAPK1	MAPK8	ENSPPYP00000023664	ENSPPYP00000002621	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase.	0.533
MAPK1	MAPK9	ENSPPYP00000023664	ENSPPYP00000018050	Mitogen-activated protein kinase 1 isoform X1.	Mitogen-activated protein kinase.	0.463
MAPK1	PTPN7	ENSPPYP00000023664	ENSPPYP00000000393	Mitogen-activated protein kinase 1 isoform X1.	PTPN7 isoform 3.	0.993
MAPK10	DUSP3	ENSPPYP00000016644	ENSPPYP00000009390	Mitogen-activated protein kinase.	Dual specificity protein phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (By similarity); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.930
MAPK10	MAPK12	ENSPPYP00000016644	ENSPPYP00000013363	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.931

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