DDX5 protein (Pongo abelii) - STRING interaction network

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALYREF	DDX17	ENSPPYP00000009820	ENSPPYP00000013186	Aly/REF export factor.	DDX17 isoform 4; Belongs to the DEAD box helicase family.	0.867
ALYREF	DDX5	ENSPPYP00000009820	ENSPPYP00000009602	Aly/REF export factor.	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	0.927
ALYREF	DHX9	ENSPPYP00000009820	ENSPPYP00000000490	Aly/REF export factor.	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	0.879
ALYREF	HNRNPH1	ENSPPYP00000009820	ENSPPYP00000018037	Aly/REF export factor.	HNRNPH1 isoform 9.	0.673
ALYREF	RBM39	ENSPPYP00000009820	ENSPPYP00000012240	Aly/REF export factor.	RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.	0.791
ALYREF	SF3B1	ENSPPYP00000009820	ENSPPYP00000014574	Aly/REF export factor.	SF3B1 isoform 1.	0.408
ALYREF	WBP11	ENSPPYP00000009820	ENSPPYP00000004936	Aly/REF export factor.	WW domain binding protein 11.	0.754
DDX17	ALYREF	ENSPPYP00000013186	ENSPPYP00000009820	DDX17 isoform 4; Belongs to the DEAD box helicase family.	Aly/REF export factor.	0.867
DDX17	DDX5	ENSPPYP00000013186	ENSPPYP00000009602	DDX17 isoform 4; Belongs to the DEAD box helicase family.	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	0.995
DDX17	DHX9	ENSPPYP00000013186	ENSPPYP00000000490	DDX17 isoform 4; Belongs to the DEAD box helicase family.	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	0.925
DDX17	DROSHA	ENSPPYP00000013186	ENSPPYP00000017166	DDX17 isoform 4; Belongs to the DEAD box helicase family.	DROSHA isoform 1.	0.885
DDX17	HNRNPH1	ENSPPYP00000013186	ENSPPYP00000018037	DDX17 isoform 4; Belongs to the DEAD box helicase family.	HNRNPH1 isoform 9.	0.868
DDX17	RBM39	ENSPPYP00000013186	ENSPPYP00000012240	DDX17 isoform 4; Belongs to the DEAD box helicase family.	RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.	0.889
DDX17	SF3B1	ENSPPYP00000013186	ENSPPYP00000014574	DDX17 isoform 4; Belongs to the DEAD box helicase family.	SF3B1 isoform 1.	0.754
DDX17	SPC24	ENSPPYP00000013186	ENSPPYP00000010733	DDX17 isoform 4; Belongs to the DEAD box helicase family.	SPC24 isoform 3.	0.438
DDX17	TP53	ENSPPYP00000013186	ENSPPYP00000008923	DDX17 isoform 4; Belongs to the DEAD box helicase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.710
DDX17	WBP11	ENSPPYP00000013186	ENSPPYP00000004936	DDX17 isoform 4; Belongs to the DEAD box helicase family.	WW domain binding protein 11.	0.868
DDX5	ALYREF	ENSPPYP00000009602	ENSPPYP00000009820	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	Aly/REF export factor.	0.927
DDX5	DDX17	ENSPPYP00000009602	ENSPPYP00000013186	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	DDX17 isoform 4; Belongs to the DEAD box helicase family.	0.995
DDX5	DHX9	ENSPPYP00000009602	ENSPPYP00000000490	Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...]	ATP-dependent RNA helicase A; Multifunctional ATP-dependent nucleic acid helicase that unwinds DNA and RNA in a 3' to 5' direction and that plays important roles in many processes, such as DNA replication, transcriptional activation, post-transcriptional RNA regulation, mRNA translation and RNA-mediated gene silencing. Requires a 3'-single-stranded tail as entry site for acid nuclei unwinding activities as well as the binding and hydrolyzing of any of the four ribo- or deoxyribo-nucleotide triphosphates (NTPs). Unwinds numerous nucleic acid substrates such as double-stranded (ds) DNA a [...]	0.989