| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42 | CDC42EP4 | ENSPPYP00000002031 | ENSPPYP00000009645 | Cell division cycle 42. | CDC42 effector protein 4. | 0.830 |
| CDC42EP4 | CDC42 | ENSPPYP00000009645 | ENSPPYP00000002031 | CDC42 effector protein 4. | Cell division cycle 42. | 0.830 |
| CDC42EP4 | SEPT3 | ENSPPYP00000009645 | ENSPPYP00000013264 | CDC42 effector protein 4. | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.939 |
| CDC42EP4 | SEPT5 | ENSPPYP00000009645 | ENSPPYP00000012920 | CDC42 effector protein 4. | SEPT5 isoform 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.922 |
| CDC42EP4 | SEPTIN10 | ENSPPYP00000009645 | ENSPPYP00000013540 | CDC42 effector protein 4. | Septin-10; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). | 0.848 |
| CDC42EP4 | SEPTIN11 | ENSPPYP00000009645 | ENSPPYP00000016596 | CDC42 effector protein 4. | Septin-11; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). | 0.939 |
| CDC42EP4 | SEPTIN14 | ENSPPYP00000009645 | ENSPPYP00000019670 | CDC42 effector protein 4. | SEPT14 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.821 |
| CDC42EP4 | SEPTIN2 | ENSPPYP00000009645 | ENSPPYP00000014937 | CDC42 effector protein 4. | Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar- shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis [...] | 0.922 |
| CDC42EP4 | SEPTIN4-2 | ENSPPYP00000009645 | ENSPPYP00000009247 | CDC42 effector protein 4. | Septin-4; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). | 0.866 |
| CDC42EP4 | SEPTIN6 | ENSPPYP00000009645 | ENSPPYP00000023140 | CDC42 effector protein 4. | SEPT6 isoform 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.862 |
| CDC42EP4 | SEPTIN8 | ENSPPYP00000009645 | ENSPPYP00000017636 | CDC42 effector protein 4. | SEPT8 isoform 13; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.939 |
| SEPT3 | CDC42EP4 | ENSPPYP00000013264 | ENSPPYP00000009645 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | CDC42 effector protein 4. | 0.939 |
| SEPT3 | SEPT5 | ENSPPYP00000013264 | ENSPPYP00000012920 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | SEPT5 isoform 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.929 |
| SEPT3 | SEPTIN10 | ENSPPYP00000013264 | ENSPPYP00000013540 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | Septin-10; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). | 0.865 |
| SEPT3 | SEPTIN11 | ENSPPYP00000013264 | ENSPPYP00000016596 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | Septin-11; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). | 0.918 |
| SEPT3 | SEPTIN14 | ENSPPYP00000013264 | ENSPPYP00000019670 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | SEPT14 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.917 |
| SEPT3 | SEPTIN2 | ENSPPYP00000013264 | ENSPPYP00000014937 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | Septin-2; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar- shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis [...] | 0.922 |
| SEPT3 | SEPTIN4-2 | ENSPPYP00000013264 | ENSPPYP00000009247 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | Septin-4; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). | 0.919 |
| SEPT3 | SEPTIN6 | ENSPPYP00000013264 | ENSPPYP00000023140 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | SEPT6 isoform 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.871 |
| SEPT3 | SEPTIN8 | ENSPPYP00000013264 | ENSPPYP00000017636 | SEPT3 isoform 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | SEPT8 isoform 13; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.922 |
