SLC9A3R1 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	EZR	ENSPPYP00000020117	ENSPPYP00000019191	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	EZR isoform 1.	0.712
CFTR	RDX	ENSPPYP00000020117	ENSPPYP00000004412	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	RDX isoform 3.	0.409
CFTR	SLC9A3R1	ENSPPYP00000020117	ENSPPYP00000009663	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.995
CR201_G0049742	SLC34A1	ENSPPYP00000022223	ENSPPYP00000018005	SLC34A3 isoform 1.	SLC34A1 isoform 3.	0.918
CR201_G0049742	SLC34A2	ENSPPYP00000022223	ENSPPYP00000016368	SLC34A3 isoform 1.	Sodium-dependent phosphate transport protein 2B; May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli (By similarity). Belongs to the SLC34A transporter family.	0.903
CR201_G0049742	SLC9A3R1	ENSPPYP00000022223	ENSPPYP00000009663	SLC34A3 isoform 1.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.942
EZR	CFTR	ENSPPYP00000019191	ENSPPYP00000020117	EZR isoform 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.712
EZR	MSN	ENSPPYP00000019191	ENSPPYP00000022855	EZR isoform 1.	MSN isoform 6.	0.999
EZR	PRKCA	ENSPPYP00000019191	ENSPPYP00000009612	EZR isoform 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.957
EZR	RDX	ENSPPYP00000019191	ENSPPYP00000004412	EZR isoform 1.	RDX isoform 3.	0.999
EZR	SLC9A3R1	ENSPPYP00000019191	ENSPPYP00000009663	EZR isoform 1.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.996
MSN	EZR	ENSPPYP00000022855	ENSPPYP00000019191	MSN isoform 6.	EZR isoform 1.	0.999
MSN	RDX	ENSPPYP00000022855	ENSPPYP00000004412	MSN isoform 6.	RDX isoform 3.	0.999
MSN	SLC9A3R1	ENSPPYP00000022855	ENSPPYP00000009663	MSN isoform 6.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.989
PRKCA	EZR	ENSPPYP00000009612	ENSPPYP00000019191	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	EZR isoform 1.	0.957
PRKCA	SLC9A3R1	ENSPPYP00000009612	ENSPPYP00000009663	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.921
PTEN	SLC9A3R1	ENSPPYP00000002838	ENSPPYP00000009663	Pongo abelii phosphatase and tensin homolog (PTEN), mRNA; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.930
RDX	CFTR	ENSPPYP00000004412	ENSPPYP00000020117	RDX isoform 3.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.409
RDX	EZR	ENSPPYP00000004412	ENSPPYP00000019191	RDX isoform 3.	EZR isoform 1.	0.999
RDX	MSN	ENSPPYP00000004412	ENSPPYP00000022855	RDX isoform 3.	MSN isoform 6.	0.999