STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPTX1Neuronal pentraxin 1. (432 aa)    
Predicted Functional Partners:
RNF2
E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, i [...]
    
 0.646
RING1
Ring finger protein 1.
    
 0.646
SLITRK2
SLITRK2 isoform 2.
   
 
 0.616
KCND2
KCND2 isoform 1; Belongs to the potassium channel family.
      
 0.565
KCND3
Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family.
      
 0.562
RCN2
RCN2 isoform 1.
    
 
 0.562
PPP1R14C
PPP1R14C isoform 1.
   
    0.548
EED
Embryonic ectoderm development.
    
 0.503
TBCD
TBCD isoform 3.
      
 0.499
GRIA1
GRIA1 isoform 7.
   
 
 0.498
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.