STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBCDTBCD isoform 3. (1192 aa)    
Predicted Functional Partners:
TBCE
Tubulin-specific chaperone E; Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network.
    
 0.921
ARL13A
ARL13A isoform 3.
    
 0.859
TBCEL
TBCEL isoform 1.
      
 0.675
CR201_G0049178
TBCB isoform 2.
    
 0.673
TBCC
Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
    
 0.637
TBCA
Tubulin-specific chaperone A; Belongs to the TBCA family.
    
 0.611
MAD1L1
Mitotic arrest deficient 1 like 1.
   
 
 0.578
CLIP1
CAP-Gly domain containing linker protein 1.
    
 
 0.576
CPN1
CPN1 isoform 1.
      
 0.576
NDC1
Nucleoporin NDC1; Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane (By similarity); Belongs to the NDC1 family.
      
 0.561
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.