| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABAT | ALDH3A1 | ENSPPYP00000008008 | ENSPPYP00000009919 | ABAT isoform 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.936 |
| ADH1A | ADH4 | ENSPPYP00000016692 | ENSPPYP00000024488 | Alcohol dehydrogenase 1A. | ADH4 isoform 4. | 0.422 |
| ADH1A | ADH7 | ENSPPYP00000016692 | ENSPPYP00000016693 | Alcohol dehydrogenase 1A. | ADH7 isoform 2. | 0.426 |
| ADH1A | ALDH3A1 | ENSPPYP00000016692 | ENSPPYP00000009919 | Alcohol dehydrogenase 1A. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.952 |
| ADH1A | CYP2E1 | ENSPPYP00000016692 | ENSPPYP00000003264 | Alcohol dehydrogenase 1A. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.941 |
| ADH1A | MAOA | ENSPPYP00000016692 | ENSPPYP00000022677 | Alcohol dehydrogenase 1A. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.916 |
| ADH1A | MAOB | ENSPPYP00000016692 | ENSPPYP00000022680 | Alcohol dehydrogenase 1A. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.918 |
| ADH4 | ADH1A | ENSPPYP00000024488 | ENSPPYP00000016692 | ADH4 isoform 4. | Alcohol dehydrogenase 1A. | 0.422 |
| ADH4 | ALDH3A1 | ENSPPYP00000024488 | ENSPPYP00000009919 | ADH4 isoform 4. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.961 |
| ADH4 | CYP2E1 | ENSPPYP00000024488 | ENSPPYP00000003264 | ADH4 isoform 4. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.937 |
| ADH4 | MAOA | ENSPPYP00000024488 | ENSPPYP00000022677 | ADH4 isoform 4. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.912 |
| ADH4 | MAOB | ENSPPYP00000024488 | ENSPPYP00000022680 | ADH4 isoform 4. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.911 |
| ADH5 | AKR1A1 | ENSPPYP00000016688 | ENSPPYP00000001636 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldo-keto reductase family 1 member A1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity). Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes. Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hypergly [...] | 0.408 |
| ADH5 | ALDH3A1 | ENSPPYP00000016688 | ENSPPYP00000009919 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.959 |
| ADH5 | CYP2E1 | ENSPPYP00000016688 | ENSPPYP00000003264 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.923 |
| ADH5 | MAOA | ENSPPYP00000016688 | ENSPPYP00000022677 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.911 |
| ADH5 | MAOB | ENSPPYP00000016688 | ENSPPYP00000022680 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.911 |
| ADH6 | ADH7 | ENSPPYP00000016690 | ENSPPYP00000016693 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | ADH7 isoform 2. | 0.411 |
| ADH6 | ALDH3A1 | ENSPPYP00000016690 | ENSPPYP00000009919 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.942 |
| ADH6 | CYP2E1 | ENSPPYP00000016690 | ENSPPYP00000003264 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.935 |
