Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGB3Integrin beta. (788 aa)    
Predicted Functional Partners:
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.999
ITGAV
ITGAV isoform 2; Belongs to the integrin alpha chain family.
   
 0.999
TLN1
TLN1 isoform 1.
   
 0.998
PTK2
PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.996
ITGA5
ITGA5 isoform 1; Belongs to the integrin alpha chain family.
   
 0.990
TLN2
TLN2 isoform 1.
   
 0.988
THBS1
Thrombospondin 1.
   
 0.987
ITGA8
ITGA8 isoform 1; Belongs to the integrin alpha chain family.
   
 0.984
VWF
VWF isoform 1.
   
 0.984
FERMT3
FERMT3 isoform 2.
   
 0.977
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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