RAB12 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP27	ARHGAP36	ENSPPYP00000009332	ENSPPYP00000023195	ARHGAP27 isoform 2.	Rho GTPase activating protein 36.	0.555
ARHGAP27	RAB12	ENSPPYP00000009332	ENSPPYP00000010115	ARHGAP27 isoform 2.	RAB12 isoform 1.	0.680
ARHGAP27	RHOBTB3	ENSPPYP00000009332	ENSPPYP00000017489	ARHGAP27 isoform 2.	RHOBTB3 isoform 7.	0.744
ARHGAP36	ARHGAP27	ENSPPYP00000023195	ENSPPYP00000009332	Rho GTPase activating protein 36.	ARHGAP27 isoform 2.	0.555
ARHGAP36	RAB12	ENSPPYP00000023195	ENSPPYP00000010115	Rho GTPase activating protein 36.	RAB12 isoform 1.	0.605
ARHGAP36	RHOBTB3	ENSPPYP00000023195	ENSPPYP00000017489	Rho GTPase activating protein 36.	RHOBTB3 isoform 7.	0.435
CHM	DENND3	ENSPPYP00000022968	ENSPPYP00000021215	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	DENND3 isoform 5.	0.606
CHM	GDI1	ENSPPYP00000022968	ENSPPYP00000023371	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.589
CHM	GDI2	ENSPPYP00000022968	ENSPPYP00000002386	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.	0.589
CHM	RAB12	ENSPPYP00000022968	ENSPPYP00000010115	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB12 isoform 1.	0.892
CHM	RABGGTB	ENSPPYP00000022968	ENSPPYP00000001430	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.983
DENND3	CHM	ENSPPYP00000021215	ENSPPYP00000022968	DENND3 isoform 5.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.606
DENND3	GDI1	ENSPPYP00000021215	ENSPPYP00000023371	DENND3 isoform 5.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.430
DENND3	GDI2	ENSPPYP00000021215	ENSPPYP00000002386	DENND3 isoform 5.	Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.	0.430
DENND3	RAB12	ENSPPYP00000021215	ENSPPYP00000010115	DENND3 isoform 5.	RAB12 isoform 1.	0.867
GDI1	CHM	ENSPPYP00000023371	ENSPPYP00000022968	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.589
GDI1	DENND3	ENSPPYP00000023371	ENSPPYP00000021215	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	DENND3 isoform 5.	0.430
GDI1	GDI2	ENSPPYP00000023371	ENSPPYP00000002386	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.	0.994
GDI1	RAB12	ENSPPYP00000023371	ENSPPYP00000010115	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB12 isoform 1.	0.897
GDI1	RABGGTB	ENSPPYP00000023371	ENSPPYP00000001430	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.716