| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DCTD | DTYMK | ENSPPYP00000017005 | ENSPPYP00000014942 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | DTYMK isoform 1. | 0.969 |
| DCTD | DUT | ENSPPYP00000017005 | ENSPPYP00000007314 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | Deoxyuridine triphosphatase. | 0.949 |
| DCTD | TK1 | ENSPPYP00000017005 | ENSPPYP00000009752 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | Thymidine kinase. | 0.971 |
| DCTD | TYMS | ENSPPYP00000017005 | ENSPPYP00000010155 | Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. | Thymidylate synthetase. | 0.986 |
| DHFR | DHFR2 | ENSPPYP00000017438 | ENSPPYP00000015237 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | 0.901 |
| DHFR | DTYMK | ENSPPYP00000017438 | ENSPPYP00000014942 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | DTYMK isoform 1. | 0.675 |
| DHFR | DUT | ENSPPYP00000017438 | ENSPPYP00000007314 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Deoxyuridine triphosphatase. | 0.442 |
| DHFR | GCSH | ENSPPYP00000017438 | ENSPPYP00000008560 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.675 |
| DHFR | GLDC | ENSPPYP00000017438 | ENSPPYP00000021533 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.719 |
| DHFR | SHMT1 | ENSPPYP00000017438 | ENSPPYP00000009057 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.980 |
| DHFR | SHMT2 | ENSPPYP00000017438 | ENSPPYP00000005336 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.969 |
| DHFR | TK1 | ENSPPYP00000017438 | ENSPPYP00000009752 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Thymidine kinase. | 0.713 |
| DHFR | TYMS | ENSPPYP00000017438 | ENSPPYP00000010155 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Thymidylate synthetase. | 0.997 |
| DHFR2 | DHFR | ENSPPYP00000015237 | ENSPPYP00000017438 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.901 |
| DHFR2 | DTYMK | ENSPPYP00000015237 | ENSPPYP00000014942 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | DTYMK isoform 1. | 0.675 |
| DHFR2 | DUT | ENSPPYP00000015237 | ENSPPYP00000007314 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Deoxyuridine triphosphatase. | 0.442 |
| DHFR2 | GCSH | ENSPPYP00000015237 | ENSPPYP00000008560 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.675 |
| DHFR2 | GLDC | ENSPPYP00000015237 | ENSPPYP00000021533 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.719 |
| DHFR2 | SHMT1 | ENSPPYP00000015237 | ENSPPYP00000009057 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.985 |
| DHFR2 | SHMT2 | ENSPPYP00000015237 | ENSPPYP00000005336 | Dihydrofolate reductase 2; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.969 |
