STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1542 aa)    
Predicted Functional Partners:
MLLT10
MLLT10 isoform 2.
    
 
 0.980
MLLT3
MLLT3 isoform 1.
    
 
 0.975
LOC100436122-8
Histone H3.1.
   
 0.957
MLLT6
MLLT6 isoform 2.
    
 
 0.941
MLLT1
MLLT1 isoform 1.
    
 
 0.939
LOC100449918
HIST2H3C isoform 1.
   
 0.919
H3C13
Histone H3.
   
 0.919
LOC100456589
Histone H2B; Belongs to the histone H2B family.
    
 
 0.909
H2AC6
Histone H2A; Belongs to the histone H2A family.
    
 
 0.881
UBC
UBC isoform 2.
   
 
 0.880
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.