SH3GL1 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

SH3GL1

SH3GL1 isoform 4. (305 aa)

Predicted Functional Partners:

GAK

0.936

CR201_G0043368

0.915

MET

0.870

MST1R

0.869

SYNJ1

0.822

SYNJ2

0.806

PDCD6IP

0.799

DPPA4

0.749

LRRK2

0.702

DNAJC6

0.700

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0043368	DNAJC6	ENSPPYP00000007649	ENSPPYP00000011932	SH3GL3 isoform 2.	DNAJC6 isoform 6.	0.700
CR201_G0043368	GAK	ENSPPYP00000007649	ENSPPYP00000016219	SH3GL3 isoform 2.	GAK isoform 7.	0.936
CR201_G0043368	LRRK2	ENSPPYP00000007649	ENSPPYP00000023875	SH3GL3 isoform 2.	LRRK2 isoform 3.	0.707
CR201_G0043368	MET	ENSPPYP00000007649	ENSPPYP00000020106	SH3GL3 isoform 2.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.913
CR201_G0043368	MST1R	ENSPPYP00000007649	ENSPPYP00000015506	SH3GL3 isoform 2.	MST1R isoform 1.	0.869
CR201_G0043368	PDCD6IP	ENSPPYP00000007649	ENSPPYP00000015692	SH3GL3 isoform 2.	PDCD6IP isoform 2.	0.663
CR201_G0043368	SH3GL1	ENSPPYP00000007649	ENSPPYP00000010546	SH3GL3 isoform 2.	SH3GL1 isoform 4.	0.915
CR201_G0043368	SYNJ1	ENSPPYP00000007649	ENSPPYP00000012687	SH3GL3 isoform 2.	SYNJ1 isoform 6.	0.812
CR201_G0043368	SYNJ2	ENSPPYP00000007649	ENSPPYP00000019180	SH3GL3 isoform 2.	SYNJ2 isoform 1.	0.757
DNAJC6	CR201_G0043368	ENSPPYP00000011932	ENSPPYP00000007649	DNAJC6 isoform 6.	SH3GL3 isoform 2.	0.700
DNAJC6	GAK	ENSPPYP00000011932	ENSPPYP00000016219	DNAJC6 isoform 6.	GAK isoform 7.	0.945
DNAJC6	LRRK2	ENSPPYP00000011932	ENSPPYP00000023875	DNAJC6 isoform 6.	LRRK2 isoform 3.	0.556
DNAJC6	MET	ENSPPYP00000011932	ENSPPYP00000020106	DNAJC6 isoform 6.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.501
DNAJC6	MST1R	ENSPPYP00000011932	ENSPPYP00000015506	DNAJC6 isoform 6.	MST1R isoform 1.	0.501
DNAJC6	SH3GL1	ENSPPYP00000011932	ENSPPYP00000010546	DNAJC6 isoform 6.	SH3GL1 isoform 4.	0.700
DNAJC6	SYNJ1	ENSPPYP00000011932	ENSPPYP00000012687	DNAJC6 isoform 6.	SYNJ1 isoform 6.	0.744
DPPA4	SH3GL1	ENSPPYP00000015167	ENSPPYP00000010546	Developmental pluripotency associated 4.	SH3GL1 isoform 4.	0.749
GAK	CR201_G0043368	ENSPPYP00000016219	ENSPPYP00000007649	GAK isoform 7.	SH3GL3 isoform 2.	0.936
GAK	DNAJC6	ENSPPYP00000016219	ENSPPYP00000011932	GAK isoform 7.	DNAJC6 isoform 6.	0.945
GAK	LRRK2	ENSPPYP00000016219	ENSPPYP00000023875	GAK isoform 7.	LRRK2 isoform 3.	0.844