| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IRAK1 | IRF3 | ENSPPYP00000023353 | ENSPPYP00000011485 | Interleukin 1 receptor associated kinase 1. | IRF3 isoform 6. | 0.555 |
| IRAK1 | IRF7 | ENSPPYP00000023353 | ENSPPYP00000003337 | Interleukin 1 receptor associated kinase 1. | IRF7 isoform 12. | 0.988 |
| IRAK1 | LY96 | ENSPPYP00000023353 | ENSPPYP00000020954 | Interleukin 1 receptor associated kinase 1. | Lymphocyte antigen 96. | 0.693 |
| IRAK1 | RIPK1 | ENSPPYP00000023353 | ENSPPYP00000018096 | Interleukin 1 receptor associated kinase 1. | Receptor interacting serine/threonine kinase 1. | 0.406 |
| IRAK1 | TICAM1 | ENSPPYP00000023353 | ENSPPYP00000010561 | Interleukin 1 receptor associated kinase 1. | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. | 0.947 |
| IRAK1 | TLR3 | ENSPPYP00000023353 | ENSPPYP00000017042 | Interleukin 1 receptor associated kinase 1. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.787 |
| IRAK1 | TLR4 | ENSPPYP00000023353 | ENSPPYP00000021908 | Interleukin 1 receptor associated kinase 1. | TLR4 isoform 1; Belongs to the Toll-like receptor family. | 0.777 |
| IRAK1 | TRAF3 | ENSPPYP00000023353 | ENSPPYP00000007003 | Interleukin 1 receptor associated kinase 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.603 |
| IRAK1 | TRAF6 | ENSPPYP00000023353 | ENSPPYP00000003845 | Interleukin 1 receptor associated kinase 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
| IRF3 | IRAK1 | ENSPPYP00000011485 | ENSPPYP00000023353 | IRF3 isoform 6. | Interleukin 1 receptor associated kinase 1. | 0.555 |
| IRF3 | IRF7 | ENSPPYP00000011485 | ENSPPYP00000003337 | IRF3 isoform 6. | IRF7 isoform 12. | 0.997 |
| IRF3 | LY96 | ENSPPYP00000011485 | ENSPPYP00000020954 | IRF3 isoform 6. | Lymphocyte antigen 96. | 0.644 |
| IRF3 | RIPK1 | ENSPPYP00000011485 | ENSPPYP00000018096 | IRF3 isoform 6. | Receptor interacting serine/threonine kinase 1. | 0.518 |
| IRF3 | RIPK3 | ENSPPYP00000011485 | ENSPPYP00000006485 | IRF3 isoform 6. | Receptor interacting serine/threonine kinase 3. | 0.412 |
| IRF3 | TICAM1 | ENSPPYP00000011485 | ENSPPYP00000010561 | IRF3 isoform 6. | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. | 0.953 |
| IRF3 | TLR3 | ENSPPYP00000011485 | ENSPPYP00000017042 | IRF3 isoform 6. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.855 |
| IRF3 | TLR4 | ENSPPYP00000011485 | ENSPPYP00000021908 | IRF3 isoform 6. | TLR4 isoform 1; Belongs to the Toll-like receptor family. | 0.741 |
| IRF3 | TRAF3 | ENSPPYP00000011485 | ENSPPYP00000007003 | IRF3 isoform 6. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.914 |
| IRF3 | TRAF6 | ENSPPYP00000011485 | ENSPPYP00000003845 | IRF3 isoform 6. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.779 |
| IRF7 | IRAK1 | ENSPPYP00000003337 | ENSPPYP00000023353 | IRF7 isoform 12. | Interleukin 1 receptor associated kinase 1. | 0.988 |
