| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C2 | C3 | ENSPPYP00000018414 | ENSPPYP00000010608 | Complement C2. | C3 isoform 1. | 0.987 |
| C2 | C4B | ENSPPYP00000018414 | ENSPPYP00000018422 | Complement C2. | C4B isoform 2. | 0.967 |
| C2 | C5 | ENSPPYP00000018414 | ENSPPYP00000021918 | Complement C2. | C5 isoform 1. | 0.739 |
| C2 | CFD | ENSPPYP00000018414 | ENSPPYP00000010432 | Complement C2. | CFD isoform 1; Belongs to the peptidase S1 family. | 0.728 |
| C2 | CFHR2 | ENSPPYP00000018414 | ENSPPYP00000000442 | Complement C2. | Complement factor H related 2. | 0.569 |
| C2 | CFI | ENSPPYP00000018414 | ENSPPYP00000016746 | Complement C2. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.704 |
| C2 | CFP | ENSPPYP00000018414 | ENSPPYP00000022718 | Complement C2. | Properdin; A positive regulator of the alternate pathway of complement (By similarity). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity). | 0.619 |
| C3 | C2 | ENSPPYP00000010608 | ENSPPYP00000018414 | C3 isoform 1. | Complement C2. | 0.987 |
| C3 | C3AR1 | ENSPPYP00000010608 | ENSPPYP00000004833 | C3 isoform 1. | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.975 |
| C3 | C4B | ENSPPYP00000010608 | ENSPPYP00000018422 | C3 isoform 1. | C4B isoform 2. | 0.983 |
| C3 | C5 | ENSPPYP00000010608 | ENSPPYP00000021918 | C3 isoform 1. | C5 isoform 1. | 0.970 |
| C3 | CFB | ENSPPYP00000010608 | ENSPPYP00000018417 | C3 isoform 1. | T0191046 isoform 1; Belongs to the peptidase S1 family. | 0.987 |
| C3 | CFD | ENSPPYP00000010608 | ENSPPYP00000010432 | C3 isoform 1. | CFD isoform 1; Belongs to the peptidase S1 family. | 0.978 |
| C3 | CFHR2 | ENSPPYP00000010608 | ENSPPYP00000000442 | C3 isoform 1. | Complement factor H related 2. | 0.981 |
| C3 | CFI | ENSPPYP00000010608 | ENSPPYP00000016746 | C3 isoform 1. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.996 |
| C3 | CFP | ENSPPYP00000010608 | ENSPPYP00000022718 | C3 isoform 1. | Properdin; A positive regulator of the alternate pathway of complement (By similarity). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity). | 0.992 |
| C3 | ITGAM | ENSPPYP00000010608 | ENSPPYP00000008263 | C3 isoform 1. | ITGAM isoform 1; Belongs to the integrin alpha chain family. | 0.979 |
| C3AR1 | C3 | ENSPPYP00000004833 | ENSPPYP00000010608 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C3 isoform 1. | 0.975 |
| C3AR1 | C4B | ENSPPYP00000004833 | ENSPPYP00000018422 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C4B isoform 2. | 0.769 |
| C3AR1 | C5 | ENSPPYP00000004833 | ENSPPYP00000021918 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C5 isoform 1. | 0.972 |
