| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOQ | ADRB3 | ENSPPYP00000016092 | ENSPPYP00000020755 | Adiponectin, C1Q and collagen domain containing. | ADRB3 isoform 1. | 0.436 |
| ADIPOQ | CFD | ENSPPYP00000016092 | ENSPPYP00000010432 | Adiponectin, C1Q and collagen domain containing. | CFD isoform 1; Belongs to the peptidase S1 family. | 0.977 |
| ADIPOQ | LEP | ENSPPYP00000016092 | ENSPPYP00000020162 | Adiponectin, C1Q and collagen domain containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.857 |
| ADIPOQ | RETN | ENSPPYP00000016092 | ENSPPYP00000010631 | Adiponectin, C1Q and collagen domain containing. | RETN isoform 2. | 0.850 |
| ADRB3 | ADIPOQ | ENSPPYP00000020755 | ENSPPYP00000016092 | ADRB3 isoform 1. | Adiponectin, C1Q and collagen domain containing. | 0.436 |
| ADRB3 | LEP | ENSPPYP00000020755 | ENSPPYP00000020162 | ADRB3 isoform 1. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.414 |
| ADRB3 | RETN | ENSPPYP00000020755 | ENSPPYP00000010631 | ADRB3 isoform 1. | RETN isoform 2. | 0.660 |
| CFD | ADIPOQ | ENSPPYP00000010432 | ENSPPYP00000016092 | CFD isoform 1; Belongs to the peptidase S1 family. | Adiponectin, C1Q and collagen domain containing. | 0.977 |
| CFD | LEP | ENSPPYP00000010432 | ENSPPYP00000020162 | CFD isoform 1; Belongs to the peptidase S1 family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.530 |
| CFD | RETN | ENSPPYP00000010432 | ENSPPYP00000010631 | CFD isoform 1; Belongs to the peptidase S1 family. | RETN isoform 2. | 0.792 |
| DHRS7C | DPP4 | ENSPPYP00000008965 | ENSPPYP00000014378 | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | DPP4 isoform 1; Belongs to the peptidase S9B family. | 0.732 |
| DHRS7C | GIPR | ENSPPYP00000008965 | ENSPPYP00000011327 | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family. | 0.717 |
| DHRS7C | PRL | ENSPPYP00000008965 | ENSPPYP00000018197 | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PRL isoform 1. | 0.633 |
| DHRS7C | RETN | ENSPPYP00000008965 | ENSPPYP00000010631 | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | RETN isoform 2. | 0.634 |
| DPP4 | DHRS7C | ENSPPYP00000014378 | ENSPPYP00000008965 | DPP4 isoform 1; Belongs to the peptidase S9B family. | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.732 |
| DPP4 | GIPR | ENSPPYP00000014378 | ENSPPYP00000011327 | DPP4 isoform 1; Belongs to the peptidase S9B family. | GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family. | 0.714 |
| DPP4 | LEP | ENSPPYP00000014378 | ENSPPYP00000020162 | DPP4 isoform 1; Belongs to the peptidase S9B family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.610 |
| DPP4 | PRL | ENSPPYP00000014378 | ENSPPYP00000018197 | DPP4 isoform 1; Belongs to the peptidase S9B family. | PRL isoform 1. | 0.633 |
| DPP4 | RETN | ENSPPYP00000014378 | ENSPPYP00000010631 | DPP4 isoform 1; Belongs to the peptidase S9B family. | RETN isoform 2. | 0.656 |
| GIPR | DHRS7C | ENSPPYP00000011327 | ENSPPYP00000008965 | GIPR isoform 4; Belongs to the G-protein coupled receptor 2 family. | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.717 |
