| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MAP2K4 | MAP2K7 | ENSPPYP00000023632 | ENSPPYP00000010648 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase 7. | 0.989 |
| MAP2K4 | MAP3K1 | ENSPPYP00000023632 | ENSPPYP00000017294 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | MAP3K1 isoform 1. | 0.998 |
| MAP2K4 | MAP3K11 | ENSPPYP00000023632 | ENSPPYP00000003540 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase kinase. | 0.484 |
| MAP2K4 | MAP3K20 | ENSPPYP00000023632 | ENSPPYP00000014446 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | MAP3K20 isoform 1. | 0.764 |
| MAP2K4 | MAP3K7 | ENSPPYP00000023632 | ENSPPYP00000018861 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.987 |
| MAP2K4 | MAPK10 | ENSPPYP00000023632 | ENSPPYP00000016644 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase. | 0.994 |
| MAP2K4 | MAPK8 | ENSPPYP00000023632 | ENSPPYP00000002621 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase. | 0.998 |
| MAP2K4 | MAPK9 | ENSPPYP00000023632 | ENSPPYP00000018050 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase. | 0.998 |
| MAP2K7 | MAP2K4 | ENSPPYP00000010648 | ENSPPYP00000023632 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | 0.989 |
| MAP2K7 | MAP3K1 | ENSPPYP00000010648 | ENSPPYP00000017294 | Mitogen-activated protein kinase kinase 7. | MAP3K1 isoform 1. | 0.995 |
| MAP2K7 | MAP3K11 | ENSPPYP00000010648 | ENSPPYP00000003540 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase kinase kinase. | 0.967 |
| MAP2K7 | MAP3K20 | ENSPPYP00000010648 | ENSPPYP00000014446 | Mitogen-activated protein kinase kinase 7. | MAP3K20 isoform 1. | 0.978 |
| MAP2K7 | MAP3K7 | ENSPPYP00000010648 | ENSPPYP00000018861 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.986 |
| MAP2K7 | MAPK10 | ENSPPYP00000010648 | ENSPPYP00000016644 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase. | 0.989 |
| MAP2K7 | MAPK8 | ENSPPYP00000010648 | ENSPPYP00000002621 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase. | 0.996 |
| MAP2K7 | MAPK8IP1 | ENSPPYP00000010648 | ENSPPYP00000003821 | Mitogen-activated protein kinase kinase 7. | MAPK8IP1 isoform 1. | 0.985 |
| MAP2K7 | MAPK8IP2 | ENSPPYP00000010648 | ENSPPYP00000013381 | Mitogen-activated protein kinase kinase 7. | MAPK8IP2 isoform 2. | 0.979 |
| MAP2K7 | MAPK9 | ENSPPYP00000010648 | ENSPPYP00000018050 | Mitogen-activated protein kinase kinase 7. | Mitogen-activated protein kinase. | 0.989 |
| MAP3K1 | MAP2K4 | ENSPPYP00000017294 | ENSPPYP00000023632 | MAP3K1 isoform 1. | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. | 0.998 |
| MAP3K1 | MAP2K7 | ENSPPYP00000017294 | ENSPPYP00000010648 | MAP3K1 isoform 1. | Mitogen-activated protein kinase kinase 7. | 0.995 |
