ADGRL1 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRA2	ADGRL1	ENSPPYP00000020751	ENSPPYP00000010804	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.598
ADGRL1	ADGRA2	ENSPPYP00000010804	ENSPPYP00000020751	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	ADGRA2 isoform 2; Belongs to the G-protein coupled receptor 2 family.	0.598
ADGRL1	FLRT3	ENSPPYP00000010804	ENSPPYP00000011984	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expres [...]	0.620
ADGRL1	FRMD6	ENSPPYP00000010804	ENSPPYP00000006604	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	FERM domain containing 6.	0.745
ADGRL1	GNB1	ENSPPYP00000010804	ENSPPYP00000002307	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.745
ADGRL1	GNB2	ENSPPYP00000010804	ENSPPYP00000019528	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	GNB2 isoform 1.	0.745
ADGRL1	GNB3	ENSPPYP00000010804	ENSPPYP00000004790	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.745
ADGRL1	GNB5	ENSPPYP00000010804	ENSPPYP00000007348	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.752
ADGRL1	TENM1	ENSPPYP00000010804	ENSPPYP00000023170	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Teneurin transmembrane protein 1.	0.572
ADGRL1	TENM2	ENSPPYP00000010804	ENSPPYP00000017931	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	TENM2 isoform 3.	0.623
ADGRL1	TENM3	ENSPPYP00000010804	ENSPPYP00000024069	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	TENM3 isoform 3.	0.564
FLRT3	ADGRL1	ENSPPYP00000011984	ENSPPYP00000010804	Leucine-rich repeat transmembrane protein FLRT3; Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (By similarity). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expres [...]	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.620
FRMD6	ADGRL1	ENSPPYP00000006604	ENSPPYP00000010804	FERM domain containing 6.	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.745
FRMD6	GNB1	ENSPPYP00000006604	ENSPPYP00000002307	FERM domain containing 6.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.736
FRMD6	GNB2	ENSPPYP00000006604	ENSPPYP00000019528	FERM domain containing 6.	GNB2 isoform 1.	0.626
FRMD6	GNB3	ENSPPYP00000006604	ENSPPYP00000004790	FERM domain containing 6.	G protein subunit beta 3.	0.489
GNB1	ADGRL1	ENSPPYP00000002307	ENSPPYP00000010804	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	ADGRL1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.745
GNB1	FRMD6	ENSPPYP00000002307	ENSPPYP00000006604	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	FERM domain containing 6.	0.736
GNB1	GNB2	ENSPPYP00000002307	ENSPPYP00000019528	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	GNB2 isoform 1.	0.989
GNB1	GNB3	ENSPPYP00000002307	ENSPPYP00000004790	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 3.	0.881