| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DOC2A | ENSPPYP00000007360 | ENSPPYP00000008194 | ENSPPYP00000007360 | Double C2-like domain-containing protein. | annotation not available | 0.514 |
| DOC2A | SNAP25 | ENSPPYP00000008194 | ENSPPYP00000011970 | Double C2-like domain-containing protein. | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. | 0.515 |
| DOC2A | UNC13A | ENSPPYP00000008194 | ENSPPYP00000010892 | Double C2-like domain-containing protein. | UNC13A isoform 4. | 0.650 |
| DOC2A | UNC13B | ENSPPYP00000008194 | ENSPPYP00000021402 | Double C2-like domain-containing protein. | UNC13B isoform 5. | 0.699 |
| DOC2A | UNC13C | ENSPPYP00000008194 | ENSPPYP00000007362 | Double C2-like domain-containing protein. | UNC13C isoform 1. | 0.477 |
| ENSPPYP00000007360 | DOC2A | ENSPPYP00000007360 | ENSPPYP00000008194 | annotation not available | Double C2-like domain-containing protein. | 0.514 |
| ENSPPYP00000007360 | RIMS1 | ENSPPYP00000007360 | ENSPPYP00000018764 | annotation not available | RIMS1 isoform 16. | 0.825 |
| ENSPPYP00000007360 | RIMS2 | ENSPPYP00000007360 | ENSPPYP00000021101 | annotation not available | Regulating synaptic membrane exocytosis 2. | 0.959 |
| ENSPPYP00000007360 | RIMS3 | ENSPPYP00000007360 | ENSPPYP00000001717 | annotation not available | RIMS3 isoform 1. | 0.722 |
| ENSPPYP00000007360 | SNAP25 | ENSPPYP00000007360 | ENSPPYP00000011970 | annotation not available | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. | 0.717 |
| ENSPPYP00000007360 | STXBP1 | ENSPPYP00000007360 | ENSPPYP00000021991 | annotation not available | Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions (By similarity). | 0.693 |
| ENSPPYP00000007360 | SYT1 | ENSPPYP00000007360 | ENSPPYP00000005465 | annotation not available | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] | 0.609 |
| ENSPPYP00000007360 | UNC13A | ENSPPYP00000007360 | ENSPPYP00000010892 | annotation not available | UNC13A isoform 4. | 0.920 |
| ENSPPYP00000007360 | UNC13B | ENSPPYP00000007360 | ENSPPYP00000021402 | annotation not available | UNC13B isoform 5. | 0.878 |
| ENSPPYP00000007360 | UNC13C | ENSPPYP00000007360 | ENSPPYP00000007362 | annotation not available | UNC13C isoform 1. | 0.898 |
| RIMS1 | ENSPPYP00000007360 | ENSPPYP00000018764 | ENSPPYP00000007360 | RIMS1 isoform 16. | annotation not available | 0.825 |
| RIMS1 | SNAP25 | ENSPPYP00000018764 | ENSPPYP00000011970 | RIMS1 isoform 16. | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. | 0.794 |
| RIMS1 | STXBP1 | ENSPPYP00000018764 | ENSPPYP00000021991 | RIMS1 isoform 16. | Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions (By similarity). | 0.773 |
| RIMS1 | SYT1 | ENSPPYP00000018764 | ENSPPYP00000005465 | RIMS1 isoform 16. | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] | 0.424 |
| RIMS1 | UNC13A | ENSPPYP00000018764 | ENSPPYP00000010892 | RIMS1 isoform 16. | UNC13A isoform 4. | 0.937 |
